Human herpesvirus 2 (HHV-2): A herpes virus that causes genital herpes, characterized by sores in the area of the genitalia. Genital herpes is a sexually transmitted disease (STD).
This virus, like human herpesvirus 1, can cause infection of the brain (encephalitis) if the immune system is severely defective or compromised. The treatment of infection with human herpesvirus 2 is by topical or oral anti-viral medication.
Human herpesvirus 2 (HHV-2) is also known as herpes simplex type 2.