Generic Name: abarelix (a BAR eh lix)Brand Names: Plenaxis
Abarelix reduces the amount of testosterone produced in the body.
Abarelix is used in the palliative treatment of advanced prostate cancer.
Abarelix may also be used for purposes other than those listed in this medication guide.
Treatment with abarelix may become less effective over time in some patients. Monitoring blood levels of testosterone will be done on a regular basis with blood tests to monitor the effectiveness of the medication.Abarelix is not intended for use by women. Abarelix is in the FDA pregnancy category X. This means that abarelix will cause birth defects in an unborn baby. Do not use this medication if you are pregnant or if you could become pregnant during treatment.
Before using abarelix, tell your doctor if you
have irregular heartbeats;
have osteoporosis; or
weigh more than 225 pounds.
You may not be able to use abarelix, or you may require a dosage adjustment or special monitoring during treatment.Abarelix is not intended for use by women. Abarelix is in the FDA pregnancy category X. This means that abarelix will cause birth defects in an unborn baby. Do not use this medication if you are pregnant or if you could become pregnant during treatment. Abarelix is not intended for use by women. It is not known whether abarelix passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.
Abarelix must be administered by a qualified healthcare provider.
Abarelix is administered as an injection into the muscle.In some cases, the use of abarelix has resulted in serious allergic reactions. An allergic reaction may occur after any injection of the medication, including, but not limited to the first dose. Patients should be observed in the doctor's office for at least 30 minutes following each dose so that immediate treatment of an allergic reaction can be obtained if needed.
Treatment with abarelix may become less effective over time in some patients. Monitoring blood levels of testosterone will be done on a regular basis with blood tests to monitor the effectiveness of the medication.
It is important to use abarelix regularly to get the most benefit.
Abarelix vials for injection should be stored at room temperature away from moisture and heat.
Contact your doctor if you miss a dose of abarelix.
An overdose of abarelix is unlikely to occur. If you do suspect that an overdose has occurred, contact your doctor, hospital emergency room, or poison control center for advice.
There are no restrictions on food, beverages, or activities while using abarelix. Follow any special instructions given by your doctor.
Other, less serious side effects may be more likely to occur. Talk to your doctor if you experience
breast enlargement or pain;
diarrhea or constipation;
changes with or difficulty urinating.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Usual Adult Dose for Prostate Cancer:
100 mg administered intramuscularly to the buttock on day 1, 15, 29 (week 4) and every 4 weeks thereafter.
It is not known whether abarelix will interact with other medicines. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products during treatment with abarelix.
Abarelix is available with a prescription under the brand name Plenaxis as an injection. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.