Trade Names:Miochol-E- Powder for solution, intraocular 20 mg
Decreases IOP by constricting pupil and stimulating ciliary muscles to open trabecular meshwork spaces and facilitate outflow of aqueous humor.
No data available.Hepatic Function Impairment
No data available.
To obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy, and other anterior segment surgery where rapid miosis may be required.
Intraocular Instill 0.5 to 2 mL into the anterior chamber before or after securing 1 or more sutures. In cataract surgery, use only after delivery of the lens.
Store at 39° to 77°F. Discard any unused solution. Do not reuse the syringe filter and discard appropriately after use. Do not gas sterilize. If blister or peelable backing is damaged or broken, sterility of the enclosed vial and ampoule cannot be assured. Open under aseptic conditions only.
There have been reports that acetylcholine has been ineffective during coadministration.
None well documented.
Bradycardia, flushing, hypotension (rare).
Corneal edema, clouding, and decompensation (infrequent).
Breathing difficulties, sweating (rare).
Category C (per Briggs' Drugs in Pregnancy and Lactation ).
Safety and efficacy not established.
Cardiovascular or bronchoconstrictor responses.
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