Antivenin (latrodectus mactans) Injection

an-tee-VEN-in (lat-roe-DEK-tus MAK-tans)

Commonly used brand name(s):

In the U.S.

  • Antivenin-Spider

Available Dosage Forms:

  • Powder for Solution
  • Injectable

Therapeutic Class: Antivenom

Uses For antivenin (latrodectus mactans)

Black widow spider antivenin belongs to a group of medicines known as immunizing agents. It is used to treat patients with serious symptoms caused by the bites of the black widow spider.

Black widow spider antivenin is to be used only by or under the supervision of a doctor.

Before Using antivenin (latrodectus mactans)

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For antivenin (latrodectus mactans), the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to antivenin (latrodectus mactans) or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of black widow spider antivenin in children with use in other age groups, antivenin (latrodectus mactans) is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of black widow spider antivenin in the elderly with use in other age groups, antivenin (latrodectus mactans) is not expected to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of antivenin (latrodectus mactans)

Dosing

The dose of antivenin (latrodectus mactans) will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of antivenin (latrodectus mactans). If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

antivenin (latrodectus mactans) Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

  • Difficulty in breathing or swallowing
  • hives
  • itching, especially of feet or hands
  • reddening of skin, especially around ears
  • swelling of eyes, face, or inside of nose
  • unusual tiredness or weakness (sudden and severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

  • Feeling of discomfort
  • fever
  • inflammation of joints
  • itching
  • muscle aches
  • rash
  • swollen lymph glands

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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