The name of your medicine is APO-Atorvastatin. It contains the active ingredient atorvastatin.
Atorvastatin lowers high cholesterol levels.
It is also used in people who have high blood pressure and coronary heart disease (CHD) or who are at risk of CHD (for example, if they have diabetes, a history of stroke, or small blood vessel disease). In these people, this medicine is used to reduce the risk of having a heart attack or stroke.
Everyone has cholesterol in their blood. It is a type of fat needed by the body for many things, such as building cell walls, making bile acids (which help to digest food) and some hormones. However, too much cholesterol can be a problem.
Cholesterol is present in many foods and is also made in your body by the liver. If your body makes too much cholesterol or you take too much cholesterol in your diet, then your level becomes too high.
High cholesterol is more likely to occur with certain diseases or if you have a family history of high cholesterol.
There are different types of cholesterol. LDL is the 'bad' cholesterol that can block your blood vessels. HDL cholesterol is the 'good' cholesterol that is thought to remove the bad cholesterol from the blood vessels.
When you have high levels of 'bad' cholesterol in your blood, it may begin to 'stick' to the inside of your blood vessels instead of being carried to the parts of the body where it is needed. Over time, this can form hard areas, also called plaque, on the walls of your blood vessels, making it more difficult for the blood to flow.
This blocking of your blood vessels can lead to several types of blood vessel disease, heart attack, angina and stroke.
There is another type of fat called triglyceride, which is a source of energy. However, high levels of triglyceride can be associated with a low level of 'good' cholesterol and may increase your risk of heart disease.
In some patients, APO-Atorvastatin is used to treat high cholesterol and high triglycerides together.
APO-Atorvastatin belongs to a group of medicines called HMG-CoA reductase inhibitors. It works by reducing the amount of cholesterol made by the liver. This medicine reduces the 'bad' cholesterol and raises the 'good' cholesterol. It also helps to protect you from a heart attack or stroke.
When you are taking APO-Atorvastatin, you also need to follow a low fat diet and other measures, such as exercise and weight control.
In most people, there are no symptoms of abnormal cholesterol or triglyceride levels. Your doctor can measure your levels with a simple blood test.
Your doctor may have prescribed this medicine for another reason.
Ask your doctor if you have any questions about why APO-Atorvastatin has been prescribed for you.
There is no evidence that this medicine is addictive.
Do not take APO-Atorvastatin if:
If you take this medicine after the expiry date has passed, it may not work or it may make you unwell.
If you are not sure whether to start taking APO-Atorvastatin, talk to your doctor.
Before you start taking this medicine, tell your doctor if:
1. You have allergies to:
2. You have or have had any medical conditions, especially the following:
3. You drink alcohol regularly.
4. You are currently pregnant or you plan to become pregnant. Do not take this medicine whilst pregnant.
5. You are currently breastfeeding or you plan to breast-feed. Do not take this medicine whilst breastfeeding.
6. You are planning to have surgery or an anaesthetic.
7. You are currently receiving or are planning to receive dental treatment.
8. You are taking or are planning to take any other medicines. This includes vitamins and supplements that are available from your pharmacy, supermarket or health food shop.
Some medicines may interfere with APO-Atorvastatin. These include:
These medicines may be affected by APO-Atorvastatin, or may affect how well it works. Your doctor or pharmacist has more information on medicines to be careful with or to avoid while taking APO-Atorvastatin.
Follow all directions given to you by your doctor carefully. These directions may differ from the information contained in this leaflet.
Take APO-Atorvastatin only when prescribed by your doctor.
Your doctor will tell you how much of this medicine you should take. This will depend on your condition and whether you are taking any other medicines.
The usual dose of APO-Atorvastatin is between 10-80 mg taken once a day.
Swallow the tablet(s) whole with a glass of water or other liquid. Do not chew or crush the tablets.
APO-Atorvastatin can be taken at any time of the day. However, your dose of APO-Atorvastatin should be taken at about the same time each day.
Taking your tablet(s) at the same time each day will have the best effect. It will also help you remember when to take the tablet(s).
APO-Atorvastatin can be taken with or without food.
Continue taking your medicine for as long as your doctor tells you.
APO-Atorvastatin helps to lower your levels of cholesterol, but it does not cure your condition. Therefore, you must continue to take it as directed by your doctor.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking your tablet(s) as you would normally.
If you are not sure whether to skip the dose, talk to your doctor or pharmacist.
Do not take a double dose to make up for the dose that you missed.
If you have trouble remembering to take your tablets, ask your pharmacist for some hints.
If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively, go to the Accident and Emergency department at your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
Tell your doctor that you are taking this medicine if:
Have your cholesterol and triglyceride levels checked when your doctor says, to make sure that is working.
Your doctor will ask you to have your liver function tested from time to time while you are taking APO-Atorvastatin to make sure the medicine is working and to prevent side effects.
Your cholesterol and triglyceride levels also need to be checked regularly while you are taking this medicine.
Go to your doctor regularly for a check-up.
Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine.
Avoid drinking large quantities of alcohol.
Drinking large quantities of alcohol may increase your chance of APO-Atorvastatin causing liver problems.
Avoid drinking large quantities of grapefruit juice.
Grapefruit juice contains one or more components that alter the metabolism of some medicines, including APO-Atorvastatin.
Drinking very large quantities (over 1.2 litres) of grapefruit juice each day increases your chance of APO-Atorvastatin causing side effects.
Be careful driving or operating machinery until you know how APO-Atorvastatin affects you.
APO-Atorvastatin generally does not cause any problems with your ability to drive a car or operate machinery. However, as with many other medicines, APO-Atorvastatin may cause dizziness in some people.
If you feel dizzy, do not drive, operate machinery or do anything else that could be dangerous.
Tell your doctor as soon as possible if you do not feel well while you are taking APO-Atorvastatin.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor to answer any questions you may have.
Tell your doctor if you notice any of the following:
These are the more common side effects, and are usually mild and short-lived.
Tell your doctor as soon as possible if you notice any of the following.
These may be serious side effects and you may need medical attention:
If you experience any of the following, stop taking your medicine and contact your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
These are very serious side effects and you may need urgent medical attention or hospitalisation:
These may be serious side effects requiring urgent medical attention. Serious side effects are rare.
Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything else that is making you feel unwell.
Do not be alarmed by the list of possible side effects. You may not experience any of them.
If you think you are having an allergic reaction to atorvastatin, do not take any more of this medicine and tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
Keep your tablets in their original packaging until it is time to take them.
If you take the tablets out of the original packaging they may not keep well.
Keep it in a cool dry place, where the temperature stays below 25°C. Do not store it or any other medicine in the bathroom or near a sink. Do not leave your tablets in the car or on windowsills.
Heat and dampness can destroy some medicines.
Keep your tablets where young children cannot reach them.
A locked cupboard at least one and a half metres off the ground is a good place to store medicines.
If your doctor tells you to stop taking APO-Atorvastatin, or the tablets have passed their expiry date, ask your pharmacist what to do with any tablets that are left over.
APO-Atorvastatin 10 mg tablets are white, oval, biconvex, film-coated tablets. Engraved "APO" on one side, "10" on the other side.
APO-Atorvastatin 20 mg tablets are white, oval, biconvex, film-coated tablets. Engraved "APO" on one side, "20" on the other side.
APO-Atorvastatin 40 mg tablets are white, oval, biconvex, film-coated tablets. Engraved "APO" on one side, "40" on the other side.
APO-Atorvastatin 80 mg tablets are white, oval, biconvex, film-coated tablets. Engraved "APO" on one side, "80" on the other side.
They are available in blister packs of 30 tablets.
Also available in bottles of 30, 100 & 500 tablets (not marketed).
The active ingredient of APO-Atorvastatin is atorvastatin (as atorvastatin calcium propylene glycol solvate).
It also contains the following inactive ingredients:
This medicine is gluten-free, lactose-free, sucrose-free, tartrazine-free and other azo dyes-free.
APO-Atorvastatin 10 mg tablets (blister pack):
AUST R 153718.
APO-Atorvastatin 10 mg tablets (bottle):
AUST R 153727.
APO-Atorvastatin 20 mg tablets (blister pack):
AUST R 153732.
APO-Atorvastatin 20 mg tablets (bottle):
AUST R 153731.
APO-Atorvastatin 40 mg tablets (blister pack):
AUST R 153738.
APO-Atorvastatin 40 mg tablets (bottle):
AUST R 153728.
APO-Atorvastatin 80 mg tablets (blister pack):
AUST R 153729.
APO-Atorvastatin 80 mg tablets (bottle):
AUST R 153730.