The name of your medicine is APO-Clopidogrel/Aspirin 75/100. It contains the active ingredients clopidogrel (as clopidogrel hydrogen sulfate) and aspirin.
It is used to prevent blood clots forming in hardened blood vessels (a process known as atherothrombosis) which can lead to events such as stroke, heart attack or death.
You may have been prescribed Clopidogrel/Aspirin to help prevent blood clots forming and to reduce the risk of heart attack, stroke or death, because you have suffered a severe type of chest pain called unstable angina, or had a heart attack.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason.
This medicine is available only with a doctor's prescription.
This medicine belongs to a group of medicines called anti-platelet medicines.
Platelets are very small blood cells which clump together during blood clotting. By preventing this clumping, anti-platelet medicines reduce the chances of blood clots forming (a process called thrombosis).
There is no evidence that this medicine is addictive.
This medicine should not be used in children as its safety and effectiveness in children have not been established.
Before you start taking this medicine, tell your doctor if:
1. You have allergies to:
2. You have or have had any medical conditions, especially the following:
3. You are currently pregnant or you plan to become pregnant. Do not take this medicine whilst pregnant until you and your doctor have discussed the risks and benefits involved.
4. You are currently breast-feeding or you plan to breast-feed. Do not take this medicine whilst breast-feeding.
5. You are planning to have surgery or an anaesthetic.
6. You are currently receiving or are planning to receive dental treatment.
7. You are taking or are planning to take any other medicines, This includes vitamins and supplements that are available from your pharmacy, supermarket or health food shop.
Some medicines may interact with Clopidogrel/Aspirin. These include:
If you are taking any of these you may need a different dose or you may need to take different medicines.
Other medicines not listed above may also interact with Clopidogrel/Aspirin.
Your doctor will have more information on medicines to avoid or be careful of while taking Clopidogrel/Aspirin.
Follow carefully all directions given to you by your doctor or pharmacist. Their instructions may be different to the information in this leaflet.
Clopidogrel/Aspirin is to be used under medical supervision only.
Your doctor will tell you how much of this medicine you should take. This will depend on your condition and whether you are taking any other medicines.
The usual dose of Clopidogrel/Aspirin is one tablet daily.
You may receive a starting dose of 300 mg clopidogrel, then one Clopidogrel/Aspirin tablet daily.
Should your doctor require you to take higher doses of aspirin you will be switched to separate tablets and no longer take Clopidogrel/Aspirin.
Do not stop taking your medicine or change your dosage without first checking with your doctor.
You should swallow the tablet with a glass of water.
Take Clopidogrel/Aspirin during or immediately after a meal.
Take this medicine at the same time each day. Taking it at the same time each day will have the best effect and will also help you remember when to take it.
Continue taking your medicine for as long as your doctor tells you.
Make sure you have enough to last over weekends and holidays.
If it is almost time to take your next dose, skip the missed dose and take your next dose at the usual time. Otherwise take it as soon as you remember and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for missed doses.
This may increase the chance of you experiencing side effects.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember.
If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively go to the Accident and Emergency Department at your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
Take Clopidogrel/Aspirin exactly as your doctor has prescribed and have any blood tests ordered by your doctor promptly.
Tell your doctor that you are taking this medicine if:
Your doctor may occasionally do tests to make sure the medicine is working and to prevent side effects. Go to your doctor regularly for a check-up.
Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine. Clopidogrel/Aspirin may increase the risk of bleeding during surgery or some dental work and treatment may need to be stopped beforehand. Your doctor will decide whether to stop Clopidogrel/Aspirin and if so, how long before surgery or dental work.
Be careful when driving or operating machinery until you know how this medicine affects you.
As with other medicines, Clopidogrel/Aspirin may cause faintness or dizziness in some people. If you drink alcohol, faintness or dizziness may be worse.
Tell your doctor as soon as possible if you do not feel well while you are taking Clopidogrel/Aspirin or if you have any questions or concerns.
Do not be alarmed by the following lists of side effects. You may not experience any of them. All medicines can have side effects. Sometimes they are serious but most of the time they are not.
Tell your doctor if you notice any of the following.
This list includes the more common side effects. Mostly, these are mild:
Tell your doctor as soon as possible if you notice any of the following.
These may be serious side effects. You may need medical attention. Most of these side effects are rare.
Other side effects not listed above may occur in some patients.
If you think you are having an allergic reaction to Clopidogrel/Aspirin, do not take any more of this medicine and tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
Keep your medicine in its original packaging until it is time to take it.
If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool dry place where the temperature will stay below 25°C and protected from moisture.
Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep this medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor or pharmacist tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely.
75mg/100mg tablets: Light pink, oval biconvex coated tablets, engraved "APO" on one side, "75-100" on the other side
Available in blister packs of 2, 4, 7, 14, 28, 30, 50, 56, 84, 98, 100, 112 and 280 tablets.
Also available in bottles of 280 tablets.
Not all strengths, pack types and/or pack sizes may be available.
Each tablet contains 75mg of Clopidogrel (as clopidogrel hydrogen sulfate) and 100mg Aspirin as the active ingredients.
It also contains the following inactive ingredients:
This medicine is gluten-free, sucrose-free, tartrazine-free and free of other azo dyes.
APO-Clopidogrel/Aspirin 75/100 tablets (blister pack): AUST R 190326
APO-Clopidogrel/Aspirin 75/100 tablets (bottles): AUST R 190325