The name of your medicine is APO-Imiquimod. It contains the active ingredient imiquimod.
It is used to treat:
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason.
This medicine is available only with a doctor's prescription.
Imiquimod is an immune response modifier. It activates immune cells in the body. The immune cells then proceed to kill and remove the virus-infected or cancer cells.
Although the exact way that imiquimod works is unknown, it is believed to be due to its effects on the immune system.
There is no evidence that this medicine is addictive.
This medicine should not be used in patients under the age of 18 years.
Do not take this medicine if:
Before you start taking this medicine, tell your doctor if:
1. You have allergies to:
2. You have or have had any medical conditions, especially the following:
3. You have previously used imiquimod cream to treat your condition.
4. You are currently pregnant or you plan to become pregnant. Do not take this medicine whilst pregnant until you and your doctor have discussed the risks and benefits involved.
5. You are currently breast-feeding or you plan to breast-feed. Do not take this medicine whilst breast-feeding until you and your doctor have discussed the risks and benefits involved.
6. You are planning to have surgery or an anaesthetic.
7. You are currently receiving or are planning to receive dental treatment.
8. You are taking or are planning to take any other medicines. This includes vitamins and supplements that are available from your pharmacy, supermarket or health food shop.
Some medicines may interact with imatinib. These include:
If you are taking any of these you may need a different dose or you may need to take different medicines.
Other medicines not listed above may also interact with imiquimod.
Follow carefully all directions given to you by your doctor. Their instructions may be different to the information in this leaflet.
Your doctor will tell you how much of this medicine you should take. This will depend on your condition and whether you are taking any other medicines.
Do not stop taking your medicine or change your dosage without first checking with your doctor.
Apply the cream as per your doctor's instructions.
Imiquimod cream is provided in single use sachets. A new sachet should be opened for each treatment, and cream from a previously opened sachet should not be used.
One sachet contains enough cream to cover a treatment area of 20 square centimetres (approximately 3 square inches).
1. Before applying the cream, wash the treatment area with mild soap and water and allow the area to dry thoroughly.
2. Apply a thin layer of cream onto the treatment area and rub it gently into the skin until it is no longer visible.
3. The cream is to be applied to the affected area prior to normal sleeping hours and should be left on the skin for approximately 8 hours (6-10 hours). During the 6-10 hours treatment period, showering or bathing should be avoided. Following the treatment period, the cream should be removed by washing the treated area with mild soap and water.
Hand washing before and after cream application is recommended.
Contact with the eyes, lips, nostrils and hairline should be avoided.
The cream should not to be applied to the affected area more than once a day.
Continue taking your medicine for as long as your doctor tells you.
Make sure you have enough to last over weekends and holidays.
If it is almost time to take your next dose, skip the missed dose and take your next dose at the usual time. Otherwise take it as soon as you remember and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for missed doses.
This may increase the chance of you experiencing side effects.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember.
If you think that you or anyone else may have used too much of this medicine, or this medicine has been accidentally swallowed, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively go to the Accident and Emergency Department at your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
Using too much imiquimod could cause severe skin reactions. If too much cream is applied, wash away the extra cream with mild soap and water.
Tell your doctor that you are taking this medicine if:
Your doctor may occasionally do tests to make sure the medicine is working and to prevent side effects.
Go to your doctor regularly for a check-up.
Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine.
Tell your doctor as soon as possible if you do not feel well while you are taking imiquimod cream or if you have any questions or concerns.
Do not be alarmed by the following lists of side effects. You may not experience any of them. All medicines can have side effects. Sometimes they are serious but most of the time they are not.
Tell your doctor if you notice any of the following:
Other side effects not listed above may occur in some patients.
If you think you are having an allergic reaction to imiquimod, do not take any more of this medicine and tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
Keep your medicine in its original packaging until it is time to take it.
If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool dry place where the temperature will stay below 25°C. Do not freeze.
Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep this medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor or pharmacist tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely.
APO-Imiquimod is a white, soft cream, packed in a single-use foil sachet.
Each sachet contains 250 mg of APO-Imiquimod cream, which is enough to cover a treatment area of 20 cm squared.
APO-Imiquimod cream is available in boxes of 1, 3, 6, 12 and 30 sachets*.
* Not all strengths, pack types and/or pack sizes may be available.
Each 250 mg of APO-Imiquimod 50 mg/g (5% w/w) cream contains 12.5 mg of imiquimod, as the active ingredient.
APO-Imiquimod cream also contains the following inactive ingredients:
This medicine is gluten-free, lactose-free, sucrose-free, tartrazine-free and free of other azo dyes.
APO-Imiquimod 50 mg/g
(5% w/w) cream:
AUST R 168101.