The name of your medicine is APO-Mycophenolate. It contains the active ingredient mycophenolate mofetil.
It is used for:
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason.
This medicine is available only with a doctor's prescription.
Mycophenolate mofetil belongs to a group of medicines called immunosuppressants.
Immunosuppressants are used to prevent rejection of transplanted organs and work by stopping your immune system from reacting to the transplanted organ.
Mycophenolate mofetil may be used together with other medicines such as cyclosporin and corticosteroids.
There is no evidence that this medicine is addictive.
Do not give mycophenolate mofetil to children under the age of 2 years.
Do not take this medicine if:
Before you start taking this medicine, tell your doctor if:
1. You have allergies to:
2. You are currently pregnant or you plan to become pregnant.
3. You are currently breast-feeding or you plan to breast-feed.
4. You have or have had any medical conditions, especially the following:
5. You have recently been vaccinated or plan to get a vaccination.
6. You are planning to have surgery or an anaesthetic.
7. You are currently receiving or are planning to receive dental treatment.
8. You are taking or are planning to take any other medicines, This includes vitamins and supplements that are available from your pharmacy, supermarket or health food shop.
Some medicines may interact with mycophenolate mofetil. These include:
If you are taking any of these you may need a different dose or you may need to take different medicines.
Other medicines not listed above may also interact with mycophenolate mofetil.
Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking this medicine.
Follow all directions given to you by your doctor or pharmacist carefully.
Their instructions may be different to the information in this leaflet.
Your doctor will tell you how much of this medicine you should take. This will depend on your condition and whether you are taking any other medicines.
Take this medicine exactly as your doctor has prescribed.
The dose to prevent organ rejection is usually 1 g to 1.5 g in the morning and 1 g to 1.5 g at night (2 g to 3 g per day) depending on which organ has been transplanted.
For renal transplant only.
For children 2 to 18 years of age, the dose to prevent rejection is dependent on your child's height and weight. The maximum dose is usually 1 g in the morning and 1 g at night (maximum 2 g daily).
Your doctor may adjust your dose depending on your response.
Do not stop taking your medicine or change your dosage without first checking with your doctor.
Swallow mycophenolate mofetil capsules whole, with a glass of water.
If a capsule breaks open accidentally, wash off any powder thoroughly with soap and water.
It is best to take doses approximately 12 hours apart. Your dose can be taken with or without food.
Take your medicine at the same time each day. Taking your medicine at the same time each day will have the best effect. It will also help you remember when to take your medicine.
Continue taking your medicine for as long as your doctor tells you.
It is important to keep taking mycophenolate mofetil to ensure your new transplant keeps working properly.
Make sure you have enough to last over weekends and holidays.
If it is almost time to take your next dose, skip the missed dose and take your next dose at the usual time. Otherwise take it as soon as you remember and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for missed doses.
This may increase the chance of you experiencing side effects.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember.
If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively go to the Accident and Emergency Department at your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
Tell your doctor that you are taking this medicine if:
Be sure to keep all of your appointments with your doctor so that your progress can be checked.
Your doctor w ill need to give you regular blood tests.
Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine.
Wear protective clothing and a broad-spectrum sunscreen when outdoors.
Medicines that prevent rejection of transplants can increase the risk of skin cancers.
Be careful driving or operating machinery until you know how this medicine affects you.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking this medicine or if you have any questions or concerns.
Do not be alarmed by the following lists of side effects. You may not experience any of them. All medicines can have side effects. Sometimes they are serious, most of the time they are not.
To stop you rejecting your organ transplant, mycophenolate mofetil reduces your body's own defence mechanisms. This means your body will not be as good at fighting infection. People taking mycophenolate mofetil, therefore develop more infections than usual.
Patients who receive immunosuppressant medicines such as mycophenolate mofetil, may also have a small increase in their risk of developing some types of cancer. You should discuss this with your doctor.
If you are over 65 years of age, you may have an increased chance of getting side effects.
Ask your doctor to answer any questions you may have.
Tell your doctor if you notice any of the following:
These are the more common side effects of mycophenolate mofetil. Mostly these are mild.
If you experience any of the following, stop taking your medicine and contact your doctor immediately or go to the Accident and Emergency department at your nearest hospital:
These are serious side effects. You may need urgent medical attention. Serious side effects are rare.
These are not complete lists of all possible side effects. Other side effects not listed above may occur in some patients.
Tell your doctor if you notice anything else that is making you feel unwell, even if it is not on these lists.
If you think you are having an allergic reaction to mycophenolate mofetil, tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
Keep your medicine in its original packaging until it is time to take it.
If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool dry place where the temperature will stay below 25°C and protect from light.
Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep this medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely.
APO-Mycophenolate 250 mg is a hard gelatine, size 1, capsule containing white to off-white powder with an opaque blue cap and an opaque pink body with 'APO' and 'M250' imprinted in black ink.
Each APO-Mycophenolate capsules contains 250 mg of mycophenolate mofetil as the active ingredient.
It also contains the following inactive ingredients:
This medicine is gluten-free, lactose-free, sucrose-free, tartrazine-free and free of other azo dyes.
APO-Mycophenolate is available in blister packs of 100 and 300 capsules and bottles of 100, 300 and 500 capsules.
Not all strengths, pack types and/or pack sizes may be available.
APO-Mycophenolate 250 mg capsules (blister pack):
AUST R 168109
APO-Mycophenolate 250 mg capsules (bottle): AUST R 168108