The name of your medicine is APO- Nifedipine XR. It contains the active ingredient, nifedipine.
It is used to treat hypertension (high blood pressure) or to prevent chronic stable angina, a type of angina.
APO-Nifedipine XR is not used for the relief of a sudden attack of angina.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason.
This medicine is available only with a doctor's prescription.
Nifedipine belongs to a group of medicines called calcium channel blockers. They work by relaxing and opening up the blood vessels in the body to lower blood pressure and to improve the supply of blood and oxygen to the heart.
APO-Nifedipine XR is designed to allow the slow release of the nifedipine from the tablet after it is taken
There is no evidence that this medicine is addictive.
There is not enough information to recommend using this medicine in children under 18 years of age.
Do not take this medicine if:
Before you start taking this medicine, tell your doctor if:
1. You have allergies to:
2. You have or have had any medical conditions, especially the following:
3. You are currently pregnant or breast-feeding or you plan to become pregnant or breast-feed. Your doctor will discuss alternative medicines with you, as you must not take nifedipine whilst pregnant or breast feeding.
4. You are planning to have surgery or an anaesthetic or are going into hospital.
5. You are currently receiving or are planning to receive dental treatment.
6. You are taking or are planning to take any other medicines, This includes vitamins and supplements that are available from your pharmacy, supermarket or health food shop.
Some medicines may interact with nifedipine. These include:
You should not eat grapefruit or drink grapefruit juice while you are taking nifedipine or for 3 days before starting to take nifedipine, because this may cause your blood pressure to drop too low.
If you are taking any of these you may need a different dose or you may need to take different medicines.
Other medicines not listed above may also interact with nifedipine.
Follow carefully all directions given to you by your doctor or pharmacist. Their instructions may be different to the information in this leaflet.
Your doctor or pharmacist will tell you how much of this medicine you should take. This will depend on your condition and whether you are taking any other medicines.
The usual starting dose is 30 mg (one 30 mg tablet) daily.
Your doctor may increase the dose slowly over several weeks depending on how you respond to this medicine. If you are being treated for high blood pressure the maximum dose is 120 mg, and if you have chronic angina, the maximum dose is 90 mg.
If a dose less than 30 mg is needed you will have to take a different brand of nifedipine.
If you have liver problems or are taking certain other medicines or you are elderly or of South Asian origin, your doctor may prescribe a lower dose.
Children under 18 years of age must not take this medicine.
Do not stop taking your medicine suddenly or change your dosage without first checking with your doctor.
Swallow the tablets whole with a glass of liquid.
Do not crush, chew or break up the tablets.
Avoid drinking grapefruit juice whilst taking this medicine.
Take this medicine at the same time each day, usually in the morning.
Taking it at the same time each day will have the best effect and will also help you remember when to take it.
It does not matter if you take it before, with or after food.
APO-Nifedipine XR helps control your condition, but does not cure it. Therefore, you must take it every day.
Continue taking your medicine for as long as your doctor tells you.
Make sure you have enough to last over weekends and holidays.
Do not stop taking the tablets suddenly unless you are told to by your doctor.
If you forget to take it and it is almost time (within 12 hours) to take your next dose, skip the missed dose and take your next dose at the usual time. Otherwise (if more than 12 hours to the next dose), take it as soon as you remember and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for missed doses.
This may increase the chance of unwanted side effects.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember.
If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively go to the Accident and Emergency Department at your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
If you take too much nifedipine, you may feel dizzy or experience flushing and fainting due to a drop in blood pressure, irregular or fast or slow heart beats; fast or troubled breathing and even loss of consciousness.
Take the tablets exactly as you are told to by your doctor.
If you do not follow your doctor's instruction you may not get control of your blood pressure or angina.
Tell your doctor if you continue to have chest pain or angina attacks or if they become more frequent while you are taking APO-Nifedipine XR.
Tell your doctor that you are taking this medicine if:
If you are taking a beta-blocker and you doctor has told you to stop taking it, make sure you gradually stop taking the beta blocker over a few days,
Your doctor may do tests to make sure the medicine is working and to prevent side effects, especially if you are taking other tablets as well or you have other medical conditions. Go to your doctor regularly for a check-up.
Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine.
Get up slowly when getting out of bed or standing up. This is to avoid becoming light-headed, dizzy or faint.
If you feel light-headed or dizzy, this may be because your blood pressure is falling suddenly. Standing up slowly, especially when you get up from sleeping or sitting, will help your body get used to the change in position and blood pressure. If this problem gets worse or continues, talk to your doctor.
Tell your doctor if, for any reason, you have not taken your medicine exactly as directed.
Otherwise, your doctor may think that it is not working and change your treatment unnecessarily.
Be careful when driving or operating machinery until you know how this medicine affects you.
Nifedipine may cause dizziness, light-headedness or fainting in some patients, especially when they first start taking the medicine, when changing the dose or in some cases when taking it with alcohol. If affected, do not drive a vehicle, operate machinery or do anything else that could be dangerous.
If you have been taking this medicine regularly for several weeks, do not suddenly stop using it.
Stopping suddenly may bring on your previous problem. Check with your doctor for the best way to reduce gradually the amount you are taking before stopping completely.
If you have angina, be careful not to overdo physical activities when you first start taking APO-Nifedipine XR.
You may feel better when you start taking it, but you will need time to improve your physical fitness.
Some self-help measures suggested below may help your condition.
Talk to your doctor or pharmacist about them:
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking APO-Nifedipine XR or if you have any questions or concerns.
Do not be alarmed by the following lists of side effects. You may not experience any of them. All medicines can have side effects. Sometimes they are serious but most of the time they are not.
Tell your doctor or pharmacist if you notice any of the following and they worry you.
This list includes the more common side effects. Mostly, these are mild:
Tell your doctor as soon as possible if you notice any of the following.
These may be serious side effects. You may need medical attention. Most of these side effects are rare.
If you experience any of the following, stop taking your medicine and contact your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
These are very serious side effects and are usually very rare. You may need urgent medical attention or hospitalisation.
If you are a man who has had problems fathering a child by in vitro fertilisation, make sure your doctor knows you are taking nifedipine. In a small number of cases of in vitro fertilisation, medicines like nifedipine seemed to have interfered with normal sperm function. This effect went away after the medicine was stopped. Nifedipine should be considered as one of the possible causes if no other explanation can be found.
Other side effects not listed above may occur in some patients.
If you think you are having an allergic reaction to APO-Nifedipine XR, do not take any more of this medicine and tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
Keep your medicine in its original packaging until it is time to take it.
If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool dry place where the temperature will stay below 25°C.
Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep this medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor or pharmacist tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely.
APO-NIFEDIPINE XR 30 mg tablets: Round, pale red tablet marked "30" on one side.
APO-NIFEDIPINE XR 60 mg tablets: Round, pale red tablet marked "60" on one side.
Available in blister packs of 30 tablets.
Not all strengths, pack types and/or pack sizes may be available.
Each tablet contains 30 mg or 60 mg of nifedipine as the active ingredient.
It also contains the following inactive ingredients:
This medicine is gluten-free, sucrose-free, tartrazine-free and free from other azo dyes.
APO-Nifedipine XR 30 mg Tablets
AUST R number 152207
APO-Nifedipine XR 60 mg Tablets
AUST R number 152208