The name of your medicine is APO-Olanzapine. It contains the active ingredient olanzapine.
It is used:
Schizophrenia is a mental illness with disturbances in thinking, feelings and behaviour. Bipolar I Disorder is a mental illness with symptoms such as feeling "high", having excessive amounts of energy, needing much less sleep than usual, talking very quickly with racing ideas and sometimes severe irritability.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason.
This medicine is available only with a doctor's prescription.
Olanzapine belongs to a group of medicines called antipsychotics. It helps to correct chemical imbalances in the brain, which may cause mental illness.
Olanzapine may be used together with other medicines such as lithium or valproate.
There is no evidence that this medicine is addictive.
Olanzapine is not recommended for use in children under the age of 18 years.
Do not take this medicine if:
Before you start taking this medicine, tell your doctor if:
1. You have allergies to:
2. You have or have had any medical conditions, especially the following:
3. You are currently pregnant or you plan to become pregnant.
4. You are currently breast-feeding or you plan to breast-feed.
5. You will be in a hot environment or do a lot of vigorous exercise.
6. You have recently been vaccinated or plan to get a vaccination.
7. You are planning to have surgery or an anaesthetic.
8. You are currently receiving or are planning to receive dental treatment.
9. You are taking or are planning to take any other medicines; this includes vitamins and supplements that are available from your pharmacy, supermarket or health food shop.
Some medicines may interact with olanzapine. These include:
Smoking may affect olanzapine or may affect how it works.
If you are taking any of these you may need a different dose or you may need to take different medicines.
Other medicines not listed above may also interact with olanzapine.
Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking this medicine.
Follow all directions given to you by your doctor or pharmacist carefully.
Their instructions may be different to the information in this leaflet.
Your doctor will tell you how much of this medicine you should take. The dose your doctor will prescribe for you will usually be in the range of 5 mg to 20 mg per day.
Your doctor may increase or decrease your dose in order to find the appropriate dose for your condition.
A lower starting dose may be prescribed for elderly patients over the age of 65 years
Do not stop taking your medicine or change your dosage without first checking with your doctor.
Do not handle the orally disintegrating tablet with wet hands. It should be handled carefully with dry hands.
Put the orally disintegrating tablet in your mouth. It will dissolve directly in your mouth, so that it can be easily swallowed.
You can also place the orally disintegrating tablet in a full glass or a cup of water, orange juice, apple juice, milk or coffee, and stir.
Drink it straight away.
With some drinks, the mixture may change colour and possibly become cloudy.
The orally disintegrating tablet should not be placed in cola drinks.
Take this medicine at the same time, once each day. Taking it at the same time each day will have the best effect and will also help you remember when to take it.
It does not matter if you take it before, with or after food.
Continue taking your medicine for as long as your doctor tells you.
Do not stop taking olanzapine just because you feel better. It is important that you do NOT stop taking olanzapine unless your doctor tells you to.
Make sure you have enough to last over weekends and holidays.
If it is almost time to take your next dose, skip the missed dose and take your next dose at the usual time.
Otherwise take it as soon as you remember and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for missed doses.
This may increase the chance of you experiencing side effects.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember.
If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively go to the Accident and Emergency Department at your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
If you have taken too much olanzapine, the most common signs are fast heartbeat, agitation/aggression, difficulty speaking, uncontrollable movements and sedation.
It is important that you remember to take olanzapine daily and at the same dose prescribed by your doctor.
Talk to your doctor or mental health professional if you have thoughts or talk about death or suicide; or thoughts or talk about self-harm or doing harm to others.
These may be signs of changes or worsening in your mental illness.
Tell your doctor if you are female and your monthly periods are absent for six months or more.
Tell your doctor that you are taking this medicine if:
Keep all of your doctor's appointments so that your progress can be checked.
Your doctor may do tests to make sure the medicine is working and to prevent side effects. Go to your doctor regularly for a check-up.
Your doctor should monitor you particularly closely in the first weeks that you start taking this medicine.
Your doctor should also monitor your weight while you are taking olanzapine.
Patients with diabetes or who have a higher chance of developing diabetes should have their blood sugar checked often.
If you are over 65, your doctor may measure your blood pressure from time to time.
Tell all doctors, dentists and pharmacists who are treating you that you are taking olanzapine.
Be careful driving or operating machinery until you know how olanzapine affects you.
Olanzapine may cause drowsiness in some people.
Be careful when drinking alcohol while taking olanzapine.
The effects of alcohol could be made worse while taking olanzapine.
Wear sunscreen and protective clothing if outside, as olanzapine may make your skin more sensitive to the sun.
Make sure you keep cool in hot weather and keep warm in cool weather.
Olanzapine may affect the way your body reacts to temperature changes
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking this medicine or if you have any questions or concerns.
Do not be alarmed by the following lists of side effects. You may not experience any of them. All medicines can have side effects. Sometimes they are serious but most of the time they are not.
Tell your doctor if you notice any of the following side effects and they worry you.
This list includes the more common side effects. Mostly, these are mild:
Some people may feel dizzy in the early stages of treatment, especially when getting up from a lying or sitting position. This side effect usually passes after taking olanzapine for a few days.
Elderly patients with dementia-related psychosis may notice the following side effects:
Some patients with Parkinson's disease may hallucinate (see, feel or hear things that are not there) or develop worsening symptoms of Parkinson's disease.
Patients with bipolar mania taking olanzapine in combination with lithium or valproate may notice the following additional side effects:
Tell your doctor if you notice any of the following side effects.
These may be serious side effects. You may need medical attention. Most of these side effects are rare.
If you experience any of the following, contact your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
These are very serious side effects and are usually very rare. You may need urgent medical attention or hospitalisation.
Also, some side effects, such as changes to liver function, cholesterol or triglycerides can occur. These can only be found when you doctor does tests from time to time to check your progress.
Do not be alarmed by this list of side effects.
You may not experience any of them.
Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything else that is making you feel unwell.
Tell your doctor if you notice anything unusual or if you are concerned about any aspect of your health, even if you think the problems are not connected with this medicine and are not referred to in this leaflet.
If you think you are having an allergic reaction to olanzapine, tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
Keep your medicine in its original packaging until it is time to take it.
If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool dry place where the temperature will stay below 25°C and protect from light.
Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep this medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely.
APO-Olanzapine ODT orally disintegrating tablets are available in the following strengths:
They are available in blister packs of 28 tablets and bottles of 28, 100 and 500 tablets.
Not all strengths, pack types and/or pack sizes may be available.
Each APO-Olanzapine ODT orally disintegrating tablets contains either 5 mg, 10 mg, 15 mg or 20 mg of olanzapine as the active ingredient.
It also contains the following inactive ingredients:
This medicine is gluten-free, lactose-free, sucrose-free, tartrazine-free and free of other azo dyes.
APO-Olanzapine ODT 5 mg orally disintegrating tablets (blister pack):
AUST R 158995
APO-Olanzapine ODT 5 mg orally disintegrating tablets (bottle):
AUST R 158989
APO-Olanzapine ODT 10 mg orally disintegrating tablets (blister pack):
AUST R 159001
APO-Olanzapine ODT 10 mg orally disintegrating tablets (bottle):
AUST R 158965
APO-Olanzapine ODT 15 mg orally disintegrating tablets (blister pack):
AUST R 158992
APO-Olanzapine ODT 15 mg orally disintegrating tablets (bottle):
AUST R 158985
APO-Olanzapine ODT 20 mg orally disintegrating tablets (blister pack):
AUST R 158986
APO-Olanzapine ODT 20 mg orally disintegrating tablets (bottle):
AUST R 158967