The name of your medicine is APO-Perindopril.
It contains the active ingredient perindopril erbumine.
Perindopril belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors.
It is used to treat high blood pressure, heart failure or stable coronary artery disease.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason.
This medicine is available only with a doctor's prescription.
Everyone has blood pressure. This pressure helps to circulate blood all around the body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have high blood pressure (also known as hypertension) when your blood pressure stays higher than is needed, even when you are calm and relaxed.
There are usually no symptoms of high blood pressure. The only way of knowing that you have it is to have your blood pressure checked on a regular basis. If high blood pressure is not treated it can lead to serious health problems. You may feel fine and have no symptoms, but eventually it can cause stroke, heart disease and kidney failure.
Perindopril helps to lower your blood pressure.
Heart failure means that the heart muscle is not pumping blood strongly enough to circulate blood around the body properly. Heart failure is not the same as a heart attack and does not mean that the heart stops working. Some people may develop heart failure after having a heart attack, but there are a number of other causes of heart failure.
Heart failure may start off with no symptoms, but as the condition progresses, you may feel short of breath or get tired easily after light physical activity such as walking. Fluid may accumulate in different parts of the body, often first noticed as swollen ankles and feet. You may also wake up short of breath at night. In severe heart failure, symptoms like breathlessness may occur even at rest.
Perindopril helps to treat heart failure. If you follow your doctor's advice, your ability to perform daily activities may improve. You may breathe more easily, feel less tired and have less swelling.
Coronary artery disease is narrowing of the vessels carrying blood to the heart. In patients with coronary artery disease, perindopril has been shown to reduce some of the risks, including heart attacks.
There is no evidence that this medicine is addictive.
This medicine should not be used in children.
Do not take this medicine if:
Tell your doctor if:
1. You have allergies to:
2. You have or have had any medical conditions, especially the following:
3. You are currently pregnant or you plan to become pregnant. Do not take this medicine whilst pregnant .
4. You are currently breastfeeding or you plan to breast-feed. Do not take this medicine whilst breastfeeding.
5. You are planning to have surgery or an anaesthetic.
6. You are currently receiving or are planning to receive dental treatment.
7. You are taking or are planning to take any other medicines. This includes vitamins and supplements that are available from your pharmacy, supermarket or health food shop.
Some medicines may interact with perindopril. These include:
If you are taking any of these you may need a different dose or you may need to take different medicines.
Other medicines not listed above may also interact with perindopril.
Follow carefully all directions given to you by your doctor. Their instructions may be different to the information in this leaflet.
Your doctor will tell you how much of this medicine you should take. This will depend on your condition and whether you are taking any other medicines.
Do not stop taking your medicine or change your dosage without first checking with your doctor.
The usual starting dose for high blood pressure or coronary artery disease is 4mg once daily, which may be increased by your doctor up to 8mg once daily
The usual starting dose for heart failure is 2mg once daily, which may be increased by your doctor up to 4mg once daily.
Elderly people can generally use perindopril safely. However, some older people have reduced kidney function, in which case the starting dose of perindopril should be 2 mg once daily. A less frequent dose may be prescribed with serious kidney failure.
Swallow your tablet(s) with a glass of water.
Take it at about the same time each day, preferably in the morning before a meal.
Taking your medicine at the same time each day will have the best effect. It will also help you remember when to take it.
Continue taking your medicine for as long as your doctor tells you.
Perindopril can help control your condition, but cannot cure it.
Make sure you have enough to last over weekends and holidays.
If it is almost time to take your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take it as soon as you remember and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for missed doses.
This may increase the chance of you experiencing side effects.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember.
If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively, go to the Accident and Emergency department at your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
If you take too much your blood pressure may fall (also known as hypotension), which can make you feel dizzy or faint.
Tell your doctor that you are taking this medicine if:
Your doctor may occasionally do tests to make sure the medicine is working and to prevent side effects. Go to your doctor regularly for a check-up.
Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine.
Be careful while driving or operating machinery until you know how perindopril affects you.
Dizziness or weakness due to low blood pressure may occur in certain patients. If you have any of these symptoms do not drive or operate machinery.
Tell your doctor as soon as possible if you do not feel well while you are taking perindopril or if you have any questions or concerns.
Do not be alarmed by the following lists of side effects. You may not experience any of them. All medicines can have side effects. Sometimes they are serious but most of the time they are not.
Tell your doctor if you notice any of the following:
Tell your doctor as soon as possible if you notice any of the following.
These may be serious side effects and you may need medical attention:
If you experience any of the following, stop taking your medicine and contact your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
These are very serious side effects and you may need urgent medical attention or hospitalisation:
Other side effects not listed above may occur in some patients.
If you think you are having an allergic reaction to perindopril, do not take any more of this medicine and tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
Keep your medicine in its original packaging until it is time to take it.
If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool, dry place where the temperature will stay below 25°C
Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep this medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely.
APO-Perindopril 2 mg tablets are white, round, biconvex tablets, engraved "APO" on one side and "PE2" on the reverse.
APO-Perindopril 4 mg tablets are white, capsule shaped, biconvex tablets, scored and engraved "PE" bisect "4" on one side, and "APO" on the reverse.
APO-Perindopril 8 mg tablets are white, capsule shaped, biconvex tablets, scored and engraved "PE" bisect "8" on one side, and "APO" on the reverse.
Each tablet contains 2 mg, 4 mg or 8 mg perindopril erbumine as the active ingredient.
It also contains the following inactive ingredients:
This medicine is gluten-free, sucrose-free, tartrazine-free and other azo dyes-free.
APO-Perindopril 2 mg tablets
Blister packs of 30 tablets.
AUST R Number 151911
APO-Perindopril 4 mg tablets
Blister packs of 30 tablets.
AUST R Number 151912
APO-Perindopril 8 mg tablets
Blister packs of 30 tablets.
AUST R Number 151913