The name of your medicine is APO-Quetiapine. It contains the active ingredient quetiapine (as quetiapine fumarate).
It is used to treat:
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason.
This medicine is available only with a doctor's prescription.
Quetiapine belongs to a group of medicines called antipsychotics.
It helps to correct chemical imbalances in the brain.
There is no evidence that this medicine is addictive.
Do not give quetiapine to children or adolescents unless recommended by your doctor.
The effects of quetiapine have only been studied in children aged between 10 and 17 years with bipolar mania and in children aged between 13 and 17 years with schizophrenia. There is not enough information on its effects in children to recommend use in other age groups or for other conditions.
Do not take this medicine if:
Do not take this medicine if you are elderly and suffer from dementia-related psychosis.
This medicine is not approved for treating this condition.
Tell your doctor if:
1. You have allergies to:
2. You have or have had any medical conditions, especially the following:
3. You are currently pregnant or you plan to become pregnant. Do not take this medicine whilst pregnant until you and your doctor have discussed the risks and benefits involved.
4. You are currently breast-feeding or you plan to breast-feed.
5. You are planning to be in a situation where your body will be subject to extreme heat or you will be exercising strenuously, or likely to suffer from dehydration.
6. You are having any blood or urine tests.
7. You are planning to have surgery or an anaesthetic.
8. You are currently receiving or are planning to receive dental treatment.
9. You are taking or are planning to take any other medicines.
Some medicines may interact with quetiapine. These include:
If you are taking any of these you may need a different dose or you may need to take different medicines.
Other medicines not listed above may also interact with quetiapine.
Follow carefully all directions given to you by your doctor or pharmacist. Their instructions may be different to the information in this leaflet.
Your doctor or pharmacist will tell you how much of this medicine you should take. This will depend on your condition and whether you are taking any other medicines.
Quetiapine fumarate is usually taken once or twice a day.
If you are elderly or if you have liver problems your doctor may prescribe a lower dose.
Do not stop taking your medicine suddenly or change your dosage without first checking with your doctor.
Swallow your tablets whole with a full glass of water.
Take this medicine at the same time each day. Taking it at the same time each day will have the best effect and will also help you remember when to take it.
It does not matter if you take it before, with or after food.
Continue taking your medicine for as long as your doctor tells you.
Quetiapine helps control your condition, but does not cure it. Therefore you must take it every day.
Do not stop taking it suddenly unless your doctor tells you to - even if you feel better.
Make sure you have enough to last over weekends and holidays.
If it is almost time to take your next dose (within 6 hours), skip the missed dose and take your next dose at the usual time. Otherwise take it as soon as you remember and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for missed doses.
This may increase the chance of you experiencing side effects.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember.
If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively go to the Accident and Emergency Department at your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
If you take too much quetiapine, you may feel drowsy, sleepy, and dizzy or have fast heart beats.
Tell your doctor that you are taking this medicine if:
Your doctor may do tests to make sure the medicine is working and to prevent side effects. Go to your doctor regularly for a check-up.
If you or someone you know is demonstrating any of the following warning signs of suicide while taking quetiapine, contact your doctor or a mental health professional immediately or go to the nearest hospital for treatment:
Occasionally, the symptoms of depression may include thoughts of suicide or self-harm. These symptoms may continue or get worse during the early stages of treatment until the effect of the medicine becomes apparent.
All mentions of suicide or violence must be taken seriously.
Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine.
Be careful while driving or operating machinery until you know how quetiapine affects you, as it may impair judgement, thinking or reactions.
If quetiapine makes you feel light-headed, dizzy or faint, be careful when getting up from a sitting or lying position. Standing up slowly, especially when you get up from bed or chairs, will help your body get used to the change in position and blood pressure. If this problem continues or gets worse, talk to your doctor.
Be careful when drinking alcohol while you are taking quetiapine. Combining your medicine and alcohol can make you more sleepy or dizzy.
Your doctor may suggest you avoid alcohol while you are being treated with this medicine.
Make sure you keep cool in hot weather and warm in cool weather. Take care also if doing strenuous exercise, and be certain to maintain your fluid levels. Quetiapine may affect the way your body reacts to temperature changes.
Avoid drinking large quantities of grapefruit juice. This medicine may be affected by grapefruit juice.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking quetiapine or if you have any questions or concerns.
Do not be alarmed by the following lists of side effects. You may not experience any of them.
All medicines can have side effects. Sometimes they are serious but most of the time they are not.
Tell your doctor or pharmacist if you notice any of the following and they worry you.
This list includes the more common side effects. Mostly, these are mild:
Tell your doctor as soon as possible if you notice any of the following.
These may be serious side effects. You may need medical attention. Most of these side effects are rare.
If you experience any of the following, stop taking your medicine and contact your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
These are very serious side effects and are usually very rare. You may need urgent medical attention or hospitalisation.
Occasionally, quetiapine may be associated with changes in your liver function or blood (e.g. blood fat levels such as cholesterol or triglycerides, blood sugar levels, thyroid hormone levels, white blood cells), which may require your doctor to do certain blood tests.
Other side effects not listed above may occur in some patients.
If you think you are having an allergic reaction to quetiapine, do not take any more of this medicine and tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
Keep your medicine in its original packaging until it is time to take it.
If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool dry place where the temperature will stay below 25°C.
Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep this medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor or pharmacist tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the remaining medicine safely.
25 mg tablets:
Peach, round, biconvex, film coated tablet. Engraved "APO" on one side, "QUE" over "25" on the other side.
Blister packs of 60 tablets.
100 mg tablets:
Yellow, round, biconvex, film coated tablet. Engraved "APO" on one side "QUE" over "100" on the other side.
Blister packs of 90 tablets.
150 mg tablets
Pale yellow, round, biconvex, film coated tablets. Engraved "APO" on one side, "QUE" over "150" on the other side.
Blister packs of 60 tablets.
200 mg tablets:
White, round, biconvex, film coated tablet. Engraved "APO" on one side, "QUE" over "200" on the other side.
Blister packs of 60 tablets.
300 mg tablets:
White, capsule shaped, biconvex film coated tablet. Engraved "APO" on one side, "QUE 300" on the other side.
Blister packs of 60 and 100 tablets.
Not all strengths, pack types and/or pack sizes may be available.
Each tablet contains 25 mg, 100 mg, 150 mg, 200 mg or 300 mg of quetiapine (as quetiapine fumarate) as the active ingredient.
It also contains the following inactive ingredients:
This medicine is gluten-free, lactose-free, sucrose-free, tartrazine-free and free of other azo dyes.
APO-Quetiapine 25 mg tablets Blister: AUST R 166082
APO-Quetiapine 100 mg tablets Blister: AUST R 166077
APO-Quetiapine 150 mg tablets Blister: AUST R 166061
APO-Quetiapine 200 mg tablets Blister: AUST R 166064
APO-Quetiapine 300 mg tablets Blister: AUST R 166059