ARIANNA is a non-steroidal aromatase inhibitor, which reduced the amount of oestrogen (female sex hormone) made by the body. In some types of breast cancer, oestrogen can help the cancer cells grow. ARIANNA may slow or stop the growth of cancer by block oestrogen.
ARIANNA is used to treat breast cancer in women who no longer have their menstrual periods either naturally, due to their age or after surgery, radiotherapy or chemotherapy.
Follow all directions given to you by your doctor.
They may differ from the information contained in this leaflet.
Ask your doctor if you have any questions about why this medicine has been prescribed for you.
Your doctor may have prescribed ARIANNA for another reason.
ARIANNA is only available with a doctor's prescription.
ARIANNA is not addictive.
Do not take ARIANNA if you are pregnant or breast-feeding.
There is a possibility of harm to the developing baby as the medicine may be absorbed within the womb.
Your baby can take in ARIANNA from breast milk if you are breast-feeding.
Do not take ARIANNA if you are allergic to:
Some of the symptoms of an allergic reaction may include skin rash, itching or hives; swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing; wheezing or shortness of breath.
Do not take ARIANNA if you are still having menstrual periods. ARIANNA should only be taken by women who are no longer having menstrual periods.
Do not take ARIANNA if you are male.
Men are not normally treated with ARIANNA.
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or show signs of tampering.
It may have no effect at all, or worse, an entirely unexpected effect if you take it after the expiry date.
If it has expired or is damaged, return it to your pharmacist for disposal.
Do not use it to treat any other complaints unless your doctor tells you to.
Do not give this medicine to anyone else.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Do not give ARIANNA to a child.
ARIANNA is not recommended for use in children.
Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.
Tell your doctor if you are pregnant or plan to become pregnant.
Tell your doctor if you are breast-feeding or plan to breast-feed.
ARIANNA should not be used during pregnancy or while breast-feeding.
Tell your doctor if you have, or have had, any medical conditions, especially the following:
Aromatase inhibitors may decrease bone mineral density (BMD) in women who have been through menopause, with a possible increased risk of fractures.
Your doctor may want to take special care if you have any of these conditions.
If you have not told your doctor about any of the above, tell him/her before you start taking ARIANNA.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Some medicines should not be taken with ARIANNA. These include:
Talk to your doctor or pharmacist if you have any concerns or questions about taking ARIANNA.
Your doctor can tell you what to do if you are taking any of these medicines.
If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking ARIANNA.
Follow all directions given to you by your doctor and pharmacist carefully.
They may differ from the information contained in this leaflet.
Your doctor or pharmacist will tell you how many tablets you will need to take each day. This depends on your condition and whether or not you are taking any other medicines.
If you do not understand the instructions on the pack, ask your doctor or pharmacist.
Always swallow the tablets whole with plenty of water.
You can take the tablets with or without food.
The usual dose is one tablet every day.
Take your ARIANNA at about the same time each day.
Taking your tablet(s) at about the same time each day will have the best effect. It will also help you remember when to take the tablets.
Swallow ARIANNA tablets whole, with a glass of water.
It does not matter whether you take ARIANNA before or after food.
Keep taking ARIANNA for as long as your doctor tells you to.
ARIANNA helps to control your condition, but does not cure it. Therefore you must take ARIANNA every day. Do not stop taking it unless your doctor tells you to, even if you feel better.
If you miss a dose, take it as soon as you remember, as long as it is 12 hours before the next dose is due. If it is less than 12 hours to the next dose, do not take the dose you have missed.
Do not take a double dose to make up for the dose you missed.
If you miss more than one dose, or are not sure what to do, check with your doctor or pharmacist.
If you have trouble remembering when to take your medicine, ask your pharmacist or doctor for some hints.
Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much ARIANNA. Do this even if there are no signs of discomfort or poisoning.
You may need urgent medical attention.
If you become pregnant while taking ARIANNA, tell your doctor immediately.
Your doctor needs to know immediately so that ARIANNA can be replaced by another medicine.
Be sure to keep all your appointments with your doctor so your progress can be checked.
Before starting any new medicine, tell your doctor, dentist or pharmacist that you are taking ARIANNA.
Tell all the doctors, dentists and pharmacists who are treating you that you are taking ARIANNA.
If you go into hospital, please let the medical staff know that you are taking ARIANNA.
Do not take ARIANNA for a longer time than your doctor has prescribed.
Do not let yourself run out of ARIANNA over the weekend or on holidays.
Do not use ARIANNA to treat any other conditions unless your doctor tells you to.
Do not give ARIANNA to anyone else, even if they have the same condition as you.
Effects on driving and operating machinery.
ARIANNA may occasionally cause drowsiness, dizziness or other symptoms which could affect your ability to drive or operate machinery. Make sure you know how you are affected by this medicine before you drive or use machinery.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking ARIANNA.
ARIANNA helps most postmenopausal women with breast cancer, but it may have unwanted side effects in some people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. Side effects may happen at the start of treatment or they may happen after you have been taking your medicine for some time. You may need medical treatment if you get some of the side effects.
If you get any side effects do not stop taking ARIANNA without first talking to your doctor or pharmacist.
Do not be alarmed by this list of possible side effects.
You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
ARIANNA may be associated with changes in your blood, urine or liver. Your doctor may want to perform tests from time to time to check on your progress and detect any unwanted side effects.
The above list includes the more common side effects of ARIANNA, some of which may disappear with continued treatment. Mostly these are mild to moderate in nature.
If any of the following happen, tell your doctor immediately or go to Accident and Emergency at the nearest hospital:
The above list includes very serious side effects. You may require urgent medical attention or hospitalisation. These side effects are rare.
Uncommon side effects can include trigger finger which is a condition in which one of your fingers or your thumb catches in a bent position. These side effects are generally mild to moderate and often resolve themselves over time.
Tell your doctor if you notice anything that is making you feel unwell.
Other side effects not listed above may also occur in some people. Tell your doctor if you notice any other effects.
Keep ARIANNA where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
Keep your tablets in the original pack until it is time to take them.
If you take the tablets out of the pack they will not keep well.
Keep your tablets in a cool dry place where the temperature stays below 25°C.
Do not store ARIANNA or any other medicine in the bathroom or near a sink.
Do not leave ARIANNA in the car or on window sills.
Heat and dampness can destroy some medicines.
If your doctor tells you to stop taking ARIANNA, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.
ARIANNA is available in 1 tablet strength:
ARIANNA comes in blister packs containing 30 tablets.
The active ingredient in ARIANNA is anastrozole.
Each ARIANNA tablet contains 1mg of anastrozole.
The tablets also contain the following inactive ingredients:
The tablets do not contain sucrose or gluten.