AVAPRO HCT is a trade name (manufacturer's name). AVAPRO HCT tablets contain two medicines, irbesartan and hydrochlorothiazide. Both these medicines are in the tablets your doctor has prescribed for you.
AVAPRO HCT lowers high blood pressure, which doctors call hypertension.
Your doctor measured your blood pressure and found it to be too high. Everyone has blood pressure. This pressure helps get your blood all around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension (high blood pressure) which means your blood pressure stays high, even when you are calm and relaxed.
There are usually no symptoms of high blood pressure. The only way of knowing that you have hypertension is to have your blood pressure checked on a regular basis. High blood pressure, if not treated, can damage blood vessels in several organs such as the heart, the kidneys, the brain and the eyes. This may lead to heart attacks, heart or kidney failure, strokes, or blindness. There are usually no symptoms of high blood pressure before damage occurs, so your doctor needs to measure your blood pressure to see if it is too high.
High blood pressure can be treated and controlled with medicines such as AVAPRO HCT. Your doctor may also have recommended that you adjust your lifestyle to help to lower your high blood pressure (losing weight, avoiding smoking, reducing alcohol consumption and restricting the amount of salt in the diet). Your doctor may also have encouraged the practice of regular, mild (not strenuous) exercise such as walking, swimming, etc.
AVAPRO HCT contains irbesartan and hydrochlorothiazide. Both medicines reduce blood pressure in different ways. Irbesartan belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin II is a substance produced in the body which causes blood vessels to tighten. Irbesartan blocks angiotensin-II and therefore relaxes your blood vessels. This helps to lower your blood pressure.
Hydrochlorothiazide belongs to the class of medicines known as diuretics. Diuretics cause an increase in the volume of urine. They also help with lowering blood pressure particularly when combined with other blood pressure reducing medicines.
Your doctor may have prescribed AVAPRO HCT for another use. If you want more information, ask your doctor.
Do not take AVAPRO HCT if:
If you are not sure if you should start taking AVAPRO HCT, talk to your doctor.
AVAPRO HCT should not be given to children.
Tell your doctor if:
Be sure you tell your doctor about any of these things before you take any AVAPRO HCT.
Tell your doctor if you are taking any other medicines, including medicines that you buy without a prescription from your pharmacy, supermarket or health food shop.
It is especially important that you tell your doctor if you are taking or plan to take any of the following: -
Your doctor will decide whether your treatment needs to be altered or whether you should have check ups more frequently.
The tablets should be taken regularly as directed by your doctor. The tablets should be swallowed with a drink of water.
AVAPRO HCT will usually be prescribed by your doctor if previous treatment does not produce a sufficient drop in your blood pressure. Your doctor will tell you how to switch from your previous treatment to AVAPRO HCT.
The usual dose of AVAPRO HCT is one tablet a day. The full blood pressure lowering effect should be reached 6-8 weeks after beginning treatment. If your blood pressure is not satisfactorily reduced with AVAPRO HCT, your doctor may prescribe another medicine to be taken with AVAPRO HCT.
Follow all directions given to you by your doctor carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the box, ask your doctor or pharmacist for help.
You should always take your daily dose of AVAPRO HCT at about the same time each day. Taking your AVAPRO HCT tablets at the same time each day will have the best effect.
It does not matter whether you take AVAPRO HCT tablets before or after food.
AVAPRO HCT helps to control your high blood pressure, but does not cure it. Therefore AVAPRO HCT must be taken every day. Continue taking AVAPRO HCT until your doctor tells you to stop.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and go back to taking your tablets as you would normally.
If you are not sure whether to skip the dose, talk to your doctor or pharmacist.
Do not take a double dose to make up for the missed dose.
If you have trouble remembering to take your tablets, ask your pharmacist for some hints.
Immediately telephone your doctor or Poisons Information Centre (telephone: 131126) or go to the Accident and Emergency Department at your nearest hospital, if you or anyone else may have taken too much AVAPRO HCT.
Do this even if there are no signs of discomfort or poisoning.
If you take too many AVAPRO HCT tablets, you will probably feel lightheaded or dizzy.
AVAPRO HCT helps most people with high blood pressure, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking AVAPRO HCT.
Tell your doctor if you notice any of the following and they worry you -
These are generally mild and do not normally require treatment to be interrupted.
Tell your doctor immediately if you notice any of the following -
These are serious side effects. Skin rash and itchiness may be symptoms of an allergic reaction.
You may need medical attention. These side effects are not common.
If any of the following happen, stop taking AVAPRO HCT and tell your doctor immediately or go to casualty at your nearest hospital -
These are serious side effects. You may need urgent medical attention or hospitalisation.
These side effects are very rare.
Other side effects not listed above may occur in some patients. If you notice any other unwanted effects, you should tell your doctor or pharmacist and ask for their advice.
Keep your AVAPRO HCT tablets in the blister pack until it is time to take them.
If you take the tablets out of the blister pack they will not keep well.
Keep AVAPRO HCT tablets in a cool dry place where the temperature stays below 25°C. Do not store AVAPRO HCT or any other medicine in the bathroom near a sink. Do not leave them near a radiator, in a car on a hot day or on a window sill.
Heat and dampness can destroy some medicines.
Keep all medicines out of the reach of children.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking AVAPRO HCT or the tablets have passed their expiry date, ask your pharmacist what to do with any tablets that are left over.
AVAPRO HCT 150/12.5 tablets - peach, oval, film-coated tablet with a heart shape on one side and "2875" on the other. Pack size: 30 tablets. AUST R 102017
AVAPRO HCT 300/12.5 tablets - peach, oval, film-coated tablet with a heart shape on one side and "2876" on the other. Pack size: 30 tablets. AUST R 102086
AVAPRO HCT 300/25 tablets - pink, oval, film-coated tablet with a heart shape on one side and "2788" on the other. Pack size: 30 tablets. AUST R 129436.
AVAPRO HCT 150/12.5 tablets - 150 mg Irbesartan and 12.5 mg Hydrochlorothiazide per tablet.
AVAPRO HCT 300/12.5 tablets - 300 mg Irbesartan and 12.5 mg Hydrochlorothiazide per tablet.
AVAPRO HCT 300/25 tablets - 300 mg Irbesartan and 25 mg Hydrochlorothiazide per tablet.
AVAPRO HCT 150/12.5 tablets and 300/12.5 tablets also contain carnauba wax, croscarmellose sodium, hypromellose, lactose, iron oxide red CI 77491, iron oxide yellow CI 77492, macrogol 3000, magnesium stearate, microcrystalline cellulose, silicon dioxide, and titanium dioxide.
AVAPRO HCT 300/25 tablets also contain carnauba wax, microcrystalline cellulose, croscarmellose sodium, lactose, magnesium stearate, silicon dioxide, pregelatinised maize starch, hypromellose, titanium dioxide, macrogol 3350 and red, yellow & black iron oxides