Azactam injection contains the active ingredient aztreonam, which is a type of medicine called an antibiotic. It is related to the penicillin/cephalosporin family of antibiotics and is used to treat infections caused by bacteria.
Aztreonam treats bacterial infections by killing the bacteria causing the infection. It does this by preventing the bacteria from forming normal cell walls. The cell walls of bacteria protect the bacterial cells and are essential for their survival. When these cell walls are not formed correctly it causes them to disintegrate and the bacteria therefore die.
Aztreonam is only effective against a specific group of bacteria, known as Gram negative bacteria. These include Pseudomonas aeruginosa, Neisseria meningitidis, and Haemophilus influenzae.
To make sure the bacteria causing an infection are susceptible to aztreonam your doctor may take a tissue sample, for example a swab from the throat or skin, or a urine or blood sample. If the bacteria causing an infection are not known, this antibiotic should be used in conjunction with another antibiotic, so that a wider range of potential infecting organisms can be targeted. When the results of microscopy and culture are known, the most appropriate antibiotic can be continued.
Aztreonam is given by injection into a vein, into a muscle in the buttock or thigh, or by drip into a vein (intravenous infusion). It is generally used to treat more serious infections.
This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines during treatment with this one, to ensure that the combination is safe.
Aztreonam may increase the anti-blood-clotting effects of anticoagulant medicines such as warfarin. If you are taking an anticoagulant, your doctor may want to perform extra monitoring of your blood clotting time while you have treatment with this medicine.
There are currently no other medicines available in the UK that contain aztreonam as the active ingredient.