Clindamycin (Zindaclin gel)
How does it work?
Zindaclin gel contains the active ingredient clindamycin phosphate, which is an antibiotic medicine.
Clindamycin is used to treat infections with bacteria. It works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. The remaining bacteria eventually die or are destroyed by the immune system. This treats the infection.
Clindamycin is active against a wide variety of bacteria, including the bacteria associated with acne, Propionebacterium acnes. This is a common type of bacteria that feeds on sebum produced by the sebaceous glands in the skin. It produces waste products and fatty acids that irritate the sebaceous glands, making them inflamed and causing spots. By controlling bacterial numbers, the inflammation of the sebaceous glands is brought under control, and the skin is allowed to heal.
It will usually take a few weeks of treatment before your skin improves.
What is it used for?
How do I use it?
- Wash the skin with a mild cleanser and pat it dry before applying the medicine.
- Zindaclin gel should be applied thinly to the affected areas of skin (not just the individual spots) once a day.
- Wash your hands after applying the medicine.
- Zindaclin gel is for external use on the skin only and must not be taken by mouth.
- Avoid getting the gel in contact with the eyes, mouth, lips and mucous membranes such as the lining of the nose. Rinse the medicine off with warm water if you accidentally get it on these areas.
- When clindamycin is taken by mouth it can sometimes cause inflammation of the bowel (colitis). Although this is very unlikely to occur when you use the antibiotic on the skin, if you get diarrhoea either during or after using this medicine, particularly if it becomes severe or persistent, or contains blood or mucus, you should stop using this medicine and consult your doctor immediately.
Use with caution in
- Sensitive skin.
- People with a history of inflammation of part of the intestines (enteritis).
- People with a history of inflammatory bowel disease, eg Crohn's disease or ulcerative colitis.
- People with a history of inflammation of the large intestine due to antibiotic treatment (antibiotic-associated colitis).
Not to be used in
- People who are allergic to clindamycin or the related antibiotic lincomycin.
- Zindaclin gel is not licensed for children under 12 years of age.
This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
- The safety of this medicine in pregnancy has not been fully established, although it is not expected to be harmful. It should be used with caution during pregnancy, and only if the benefits to the mother outweigh any potential risks to the developing baby. Seek further medical advice from your doctor.
- It is not known if this medicine passes into breast milk after application to the skin. Clindamycin does pass into breast milk when taken by mouth. For this reason this medicine should be used with caution during breastfeeding and only if the benefits to the mother outweigh any possible risk to the nursing infant. If you do use this medicine while breastfeeding make sure you do not apply it to areas where it could be ingested by the baby or transferred to the baby's skin while you are feeding. Stop using the medicine and consult your doctor if the child develops diarrhoea while you are using this medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Common (affect between 1 in 10 and 1 in 100 people)
- Dry skin.
- Skin irritation, such as redness, itching or burning sensation.
- Eye irritation.
- Worsening of acne.
Uncommon (affect between 1 in 100 and 1 in 1000 people)
- Painful skin.
- Scaly rash.
- Inflammation of the intestine and diarrhoea, including bloody diarrhoea and stomach pain (see warning section above).
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines?
Clindamycin is not known to affect other medicines when applied to the skin. However, as with all medicines, it is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start using this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while using this one, to make sure that the combination is safe.
If you find that this medicine dries or irritates your skin, then using other skin preparations (such as medicated cosmetics, soaps, cleansers, toiletries and other anti-acne preparations, particularly those containing benzoyl peroxide or high concentrations of alcohol or astringents), is likely to make this worse.
Other medicines containing the same active ingredient
- Dalacin C capsules.
- Dalacin cream.
- Dalacin T topical solution and lotion.