Daktacort cream and ointment contain two active ingredients, hydrocortisone and miconazole.
Hydrocortisone is a type of medicine known as a corticosteroid (or steroid). Corticosteroids are hormones that are produced naturally by the adrenal glands, and have many important functions, including control of inflammatory responses.
Hydrocortisone is the same as the natural corticosteroid, cortisol, and is used to decrease inflammation in the skin. When applied to the skin it is absorbed into the skin cells. Here it works by preventing the release of certain chemicals from the cells. These chemicals are important in the immune system, and are released as a result of allergy or irritation. They cause blood vessels to widen, resulting in the affected area of skin becoming red, swollen, itchy and painful, as seen in dermatitis or eczema. By decreasing the release of these chemicals in the skin, hydrocortisone reduces inflammation and thus relieves redness, swelling and itching.
There is a range of potencies of corticosteroids applied to the skin. Hydrocortisone is classed as a mild corticosteroid. It is used to treat a wide variety of inflammatory skin disorders such as eczema and dermatitis.
Miconazole is a type of antifungal medicine known as an imidazole. It kills fungi, yeasts and some bacteria. Miconazole works by preventing fungi from producing a substance called ergosterol, which is a component of fungal cell membranes. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. Without ergosterol as part of the cell membrane, the membrane is weakened and damaged, and essential constituents of the fungal cells can leak out. This kills the fungi. Miconazole is used to treat infections with fungi and certain types of bacteria (Staphylococcus and Streptococcus species).
The combination of hydrocortisone and miconazole in Daktacort is used to treat inflammatory skin disorders, such as eczema, that have become infected. The hydrocortisone reduces the inflammation while the miconazole treats the infection. Once the inflammation is reduced (usually after about seven days) your doctor may prescribe a medicine containing just an antifungal, eg Daktarin cream or Daktarin powder to treat any remaining infection.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Tell your doctor or pharmacist what medicines you are already using, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before using any new medicines while using this one, to make sure that the combination is safe.
Miconazole is unlikely to be absorbed through the skin in sufficient amounts to affect other medicines that you are taking by mouth. However, if you are taking warfarin to prevent blood clots, there is a very small chance that this medicine may enhance the effect of the warfarin. If you are taking warfarin your doctor may therefore want to monitor your blood-clotting time (INR) during and after a course of this medicine.
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