Daktacort hydrocortisone cream (Hydrocortisone, miconazole)

How does it work?

Daktacort hydrocortisone cream contains two active ingredients, miconazole and hydrocortisone.

Miconazole is a type of antifungal medicine. It kills fungi, yeasts and some bacteria (Staphylococcus and Streptococcus species). Miconazole works by preventing fungi from producing a substance called ergosterol, which is a component of fungal cell membranes. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. Without ergosterol as part of the cell membrane, the membrane is weakened and damaged, and essential constituents of the fungal cells can leak out. This kills the fungi.

Hydrocortisone is a type of medicine known as a corticosteroid (or steroid). Corticosteroids are hormones that are produced naturally by the adrenal glands and have many important functions, including control of inflammatory responses. Hydrocortisone is used to decrease inflammation in the skin. When applied to the skin it is absorbed into the skin cells. Here it works by preventing the release of certain chemicals from the cells. These chemicals are important in the immune system, and are released as a result of irritation. They cause blood vessels to widen, resulting in the affected area of skin becoming red, swollen, itchy and painful. By decreasing the release of these chemicals in the skin, hydrocortisone reduces inflammation and thus relieves swelling, redness and itching.

The combination of medicines in Daktacort hydrocortisone cream is used to treat a fungal infection of the skin on the feet called athlete's foot, and another fungal infection of the skin called Candidal intertrigo. This occurs between folds of skin or areas of skin that rub together, eg between the buttocks or thighs, or beneath the breasts, and is due to overgrowth of Candida species of fungi in these warm, moist areas. The miconazole in this medicine kills the fungi causing these infections, while the hydrocortisone reduces the associated inflammation and relieves redness, swelling and itching.

When the inflammation (redness and itching) of these conditions has cleared up, treatment of the infection can be continued with a medicine containing just an antifungal.

What is it used for?

  • Inflamed athlete's foot (tinea pedis).
  • Infection and inflammation between folds of skin due to overgrowth of Candida fungi (Candidal intertrigo, sometimes known as sweat rash).

If you have a fungal infection without any symptoms of inflammation, an antifungal medication without hydrocortisone may be more appropriate for you. Ask your doctor or pharmacist if you are in doubt.

How do I use it?

Daktacort hydrocortisone cream should be applied to the affected areas of skin and rubbed in gently twice a day for up to seven days.

Once the inflammation (redness and itching) of these conditions has cleared up, treatment of the infection can be continued with a medicine containing just an antifungal, eg Daktarin cream or Daktarin powder.

Warning!

  • This cream is for external use on the skin only.
  • Wash and dry the skin thoroughly before applying the cream. Wash your hands after applying the cream to avoid spreading the infection to other areas of the body, or to other people.
  • Do not apply the cream to broken areas of skin.
  • Do not apply this cream to the face, and avoid getting it in contact with your eyes and the moist membranes lining the inside of certain parts of the body, eg mouth, nasal passages (mucous membranes).
  • Avoid using this cream on large areas of skin, as this may result in absorption of sufficient quantities of the medicine into the body to cause side effects.
  • You should not cover the area being treated with airtight dressings such as bandages or other dressings unless directed by a doctor, as these will enhance the absorption of the medicine into the body and may increase the risk of side effects.
  • Do not use this medicine for longer than seven days. If symptoms persist after this time, seek medical advice from your pharmacist or doctor.

Not to be used in

  • Children under the age of ten years, unless prescribed by a doctor.
  • Skin conditions that have become secondarily infected, unless prescribed by a doctor.
  • Genital or anal areas, unless prescribed by a doctor.
  • Broken skin or open wounds.
  • Areas of skin affected by acne.
  • Cold sores (herpes simplex virus).
  • Ringworm infections, unless prescribed by a doctor.
  • Skin infections caused by Gram-negative types of bacteria.
  • Tuberculosis infection of the skin.
  • Viral skin infections such as chickenpox or herpes simplex.

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

  • This medicine should not be used during pregnancy unless considered essential by your doctor. If it is prescribed by your doctor it should not be used on large areas of skin, underneath airtight dressings, or for prolonged periods of time. Consult your doctor for further information.
  • This medicine should not be used during breastfeeding unless considered essential by your doctor. If it is prescribed by your doctor it should not be used on large areas of skin, underneath airtight dressings or for prolonged periods of time. If it is applied to the breasts it should be washed off carefully before breastfeeding and then reapplied afterwards.

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

  • Skin irritation, eg redness, itching, burning sensation or rash in area of use. If affected stop using this medicine.

The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

Tell your doctor or pharmacist what medicines you are already using, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before using any new medicines while using this one, to make sure that the combination is safe.

Miconazole is unlikely to be absorbed through the skin in sufficient amounts to affect other medicines that you are taking by mouth. However, if you are taking warfarin to prevent blood clots, there is a very small chance that this medicine may enhance the effect of the warfarin. If you are taking warfarin your doctor may therefore want to monitor your blood-clotting time (INR) during and after a course of this medicine.

Other medicines containing the same active ingredients

Daktacort cream/ointment