Daktacort hydrocortisone cream contains two active ingredients, miconazole and hydrocortisone.
Miconazole is a type of antifungal medicine. It kills fungi, yeasts and some bacteria (Staphylococcus and Streptococcus species). Miconazole works by preventing fungi from producing a substance called ergosterol, which is a component of fungal cell membranes. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. Without ergosterol as part of the cell membrane, the membrane is weakened and damaged, and essential constituents of the fungal cells can leak out. This kills the fungi.
Hydrocortisone is a type of medicine known as a corticosteroid (or steroid). Corticosteroids are hormones that are produced naturally by the adrenal glands and have many important functions, including control of inflammatory responses. Hydrocortisone is used to decrease inflammation in the skin. When applied to the skin it is absorbed into the skin cells. Here it works by preventing the release of certain chemicals from the cells. These chemicals are important in the immune system, and are released as a result of irritation. They cause blood vessels to widen, resulting in the affected area of skin becoming red, swollen, itchy and painful. By decreasing the release of these chemicals in the skin, hydrocortisone reduces inflammation and thus relieves swelling, redness and itching.
The combination of medicines in Daktacort hydrocortisone cream is used to treat a fungal infection of the skin on the feet called athlete's foot, and another fungal infection of the skin called Candidal intertrigo. This occurs between folds of skin or areas of skin that rub together, eg between the buttocks or thighs, or beneath the breasts, and is due to overgrowth of Candida species of fungi in these warm, moist areas. The miconazole in this medicine kills the fungi causing these infections, while the hydrocortisone reduces the associated inflammation and relieves redness, swelling and itching.
When the inflammation (redness and itching) of these conditions has cleared up, treatment of the infection can be continued with a medicine containing just an antifungal.
If you have a fungal infection without any symptoms of inflammation, an antifungal medication without hydrocortisone may be more appropriate for you. Ask your doctor or pharmacist if you are in doubt.
Daktacort hydrocortisone cream should be applied to the affected areas of skin and rubbed in gently twice a day for up to seven days.
Once the inflammation (redness and itching) of these conditions has cleared up, treatment of the infection can be continued with a medicine containing just an antifungal, eg Daktarin cream or Daktarin powder.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Tell your doctor or pharmacist what medicines you are already using, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before using any new medicines while using this one, to make sure that the combination is safe.
Miconazole is unlikely to be absorbed through the skin in sufficient amounts to affect other medicines that you are taking by mouth. However, if you are taking warfarin to prevent blood clots, there is a very small chance that this medicine may enhance the effect of the warfarin. If you are taking warfarin your doctor may therefore want to monitor your blood-clotting time (INR) during and after a course of this medicine.