dif-THEER-ee-a TOX-oyd, ad-SORBD, TET-n-us TOX-oyd, per-TUS-iss vak-seen, a-SELL-yoo-lar, hep-ah-TY-tiss B vak-seen re-KOM-bin-ant, POE-lee-oh VYE-rus vak-SEEN, in-AK-ti-vated
Commonly used brand name(s):
In the U.S.
Available Dosage Forms:
Therapeutic Class: Vaccine
Diphtheria and tetanus toxoids and pertussis vaccine (also known as DTP vaccine) combined with hepatitis B and poliovirus vaccine (also known as HepB and IPV) is a combination immunizing agent used to prevent illness caused by diphtheria, tetanus, pertussis, hepatitis B, and poliovirus. The vaccine works by causing the body to produce its own protection (antibodies) against these diseases.
This vaccine combines five agents into one vaccine. In order to complete the series, you must get three injections of this vaccine at separate intervals. Because there are many different diseases you will need to be vaccinated against, be sure to follow your doctor's directions about your vaccination schedule.
Diphtheria is a serious illness that can cause breathing difficulties, heart problems, nerve damage, pneumonia, and possibly death. The risk of serious complications is greater in very young children and the elderly.
Tetanus (also known as lockjaw) is a very serious illness that causes seizures and severe muscle spasms that can be strong enough to cause bone fractures of the spine. The disease continues to occur almost exclusively among people who do not get vaccinated or do not have enough protection from previous vaccines.
Pertussis (also known as whooping cough) is a serious disease that causes severe spells of coughing that can interfere with breathing. Pertussis can also cause pneumonia, long lasting bronchitis, seizures, brain damage, and death.
Hepatitis B infection is a major cause of serious liver diseases including liver cancer. You get hepatitis B by being exposed to someone else's body fluids. Pregnant women can also give hepatitis B to their unborn child. People who have the virus can give it to others without them knowing it.
Polio is a very serious infection that causes paralysis of the muscles, including the muscles that enable you to walk and breathe. A polio infection may leave a person unable to breathe without the help of a breathing machine. It may also leave a person unable to walk without leg braces or being confined to a wheelchair. There is no cure for polio.
In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:
In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For DTaP-HepB-IPV vaccine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to diphtheria, tetanus, acellular pertussis, hepatitis b, polio vaccine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Safety and effectiveness have not been established in children younger than six weeks of age. This vaccine is also not recommended for children over seven years of age.
DTaP-HepB-IPV is not approved for use in older adults.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:
The dose of diphtheria, tetanus, acellular pertussis, hepatitis b, polio vaccine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of diphtheria, tetanus, acellular pertussis, hepatitis b, polio vaccine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
It is very important that your doctor check you at regular visits. Be sure to notify your doctor or clinic of any side effects that occur after you have received the vaccination. It is very important that you return to your doctor for the next dose in the series.
Along with its needed effects, a vaccine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. It is very important that you tell your doctor about any side effect that occurs after a dose of DTaP-HepB-IPV vaccine, even if the side effect goes away without treatment. Some types of side effects may mean that your child should not receive any more doses of DTaP-HepB-IPV vaccine.
Check with your doctor immediately if any of the following side effects occur:Incidence not determined
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More Common
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Incidence not determined
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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