Emcor tablets and Emcor LS tablets contain the active ingredient bisoprolol, which is a type of medicine called a beta-blocker. (NB. Bisoprolol is also available without a brand name, ie as the generic medicine.)
Beta-blockers work by blocking beta receptors that are found in various parts of the body. Blocking beta receptors prevents the action of two chemicals, called noradrenaline and adrenaline, which are produced naturally by the body. These are often referred to as the 'fight or flight' chemicals, because they are responsible for the body's reaction to stressful situations.
Beta receptors are found in the heart. When they are blocked by bisoprolol, this reduces the effect of adrenaline and noradrenaline on the heart. As a result, the heart beats more slowly and with less force. This reduces the pressure at which the blood is pumped out of the heart and around the body, which in turn reduces the blood pressure. This means that bisoprolol can be used to treat high blood pressure.
When the heart beats slower and with less force, this also reduces the energy used by the heart to pump blood around the body. This reduces the heart's need for oxygen, which means bisoprolol can also be used in the management of angina.
Angina is chest pain that occurs because the heart does not get enough oxygen to meet demand, such as when doing exercise. Bisoprolol reduces the workload of the heart and so decreases its demand for oxygen. This helps to prevent attacks of angina.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
In people with diabetes, bisoprolol can prolong the lowering of blood sugar (hypoglycaemia) caused by insulin or other antidiabetic medicines. People with diabetes should monitor their blood sugar, as bisoprolol can also mask the signs of hypoglycaemia.
If bisoprolol is taken in combination with calcium channel blockers such as verapamil, nifedipine or diltiazem, there may be an increased risk of slow heart rate, low blood pressure and heart failure. Verapamil and diltiazem are not recommended for use in combination with bisoprolol.
If bisoprolol is taken in combination with clonidine to lower blood pressure, there is a risk of a rebound increase in blood pressure if the clonidine is stopped. To avoid this, the bisoprolol should be stopped several days before slowly stopping the clonidine.
There may be an increased risk of a slow heart rate if bisoprolol is taken with the following medicines:
Non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin may reduce the blood pressure lowering effects of bisoprolol.
If bisoprolol is taken in combination with ergotamine or dihydroergotamine there may be an increased risk of blood circulation problems in the extremities (cold hands and feet).
Bisoprolol has an additive effect with other medicines that decrease blood pressure, particularly medicines used to treat high blood pressure (antihypertensives). Other medicines that decrease blood pressure include the following:
The antibiotic rifampicin may decrease the blood level of bisoprolol.
Bisoprolol tablets and oral solution are also available without a brand name, ie as the generic medicine.