NeoRecormon injection contains the active ingredient epoetin beta, which is a synthetic version of the naturally-occurring hormone erythropoietin. Erythropoietin is produced by healthy kidneys. It stimulates the bone marrow to produce red blood cells, which carry oxygen around the body.
Epoetin beta is used to treat anaemia in people with chronic kidney failure who are undergoing dialysis, and in people with impaired kidney function who do not yet need dialysis. These people produce very little erythropoietin as a result of their kidney disease, so the number of red blood cells in their blood is low (anaemia). When epoetin beta is injected, it stimulates the bone marrow to produce more red blood cells, and this corrects the anaemia.
Epoetin beta is also used to treat anaemia in people with certain types of cancer. It is used to treat anaemia in adults with solid tumours who are receiving platinum-based chemotherapy. It is also used to treat anaemia in people with non-Hodgkins lymphoma, bone marrow cancer (multiple myeloma) or chronic lymphocytic leukaemia who are receiving anti-tumour therapy. The increased red blood cell production stimulated by epoetin beta reduces the chances of these people needing a blood transfusion.
Premature babies born at less than 34 weeks gestation may also be given epoetin beta to stimulate the production of red blood cells and prevent the development of anaemia.
Doctors may also prescribe epoetin beta for anaemic people who are going to donate blood prior to surgery so that their own blood can be given to them during or after surgery. This is called an autologous blood pre-donation programme. Because the epoetin increases blood cell production, it means that a larger volume of blood can be taken from these people, and stored for transfusion during or after the surgery.
Your doctor may also prescribe you iron supplements while you are receiving this medicine so that the body has adequate iron stores for producing new red blood cells.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
If you are receiving haemodialysis to treat kidney failure you may need an increased dose of heparin while using this medicine. This is because epoetin increases the volume of cells in the blood and may therefore increase the risk of blood clotting in the dialysis system.
There are currently no other medicines available in the UK that contain epoetin beta as the active ingredient.