Pepcidtwo chewable tablets contain three active ingredients, famotidine, magnesium hydroxide and calcium carbonate. These are all medicines that reduce acidity in the stomach.
Famotidine is a type of medicine called an H2 receptor antagonist. It works by blocking H2 receptors that are found on the cells in the stomach lining. A natural body chemical called histamine normally binds to these receptors, causing the cells to produce stomach acid. By blocking the H2 receptors, famotidine prevents histamine from binding to them. This stops the cells from producing stomach acid.
Stomach acid is present as a normal part of the digestive process. However, if large amounts of stomach acid are produced this can cause pain in the abdomen, commonly known as indigestion. The excess acid may also flow back into the food pipe (oesophagus) causing pain and a burning sensation known as heartburn. Famotidine decreases the amount of acid produced by the stomach, and as a result helps relieve the symptoms of indigestion and heartburn.
Magnesium hydroxide and calcium carbonate are medicines called antacids. They work by binding to excess acid produced by the stomach. This neutralises the acid and decreases the acidity of the stomach contents.
These medicines work in combination to reduce stomach acidity, and therefore relieve indigestion and heartburn. The antacids reduce the acidity as soon as they reach the stomach, while famotidine has a more prolonged effect, decreasing acidity for up to 12 hours.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
If you are already taking any other medicines, including those bought without a prescription and herbal medicines, it is important to check with your pharmacist before taking this one as well, to make sure that the combination is safe.
Antacids, including calcium carbonate and magnesium hydroxide, may affect the absorption from the gut of various other medicines. If you are taking any other medicines, consult your doctor or pharmacist before taking this medicine. In general, any interactions can be avoided by leaving an interval of about two hours between taking this medicine and any other medicine.
As famotidine lowers the acidity in the gut it may reduce the absorption of the following medicines, which could make them less effective:
Ask your pharmacist for advice if you are taking any of these.
This medicine should not be taken by people who are having histamine treatment for leukaemia, because famotidine may theoretically make the histamine less effective.
There are currently no other medicines available in the UK that contain this combination of active ingredients.
Famotidine is available on its own and there are various antacid medicines available that contain magnesium hydroxide and calcium carbonate.