Canesten oral capsule contains the active ingredient fluconazole, which is an antifungal medicine used to treat infections with fungi and yeasts. Canesten oral capsule is a single dose treatment for vaginal thrush. It can also be used to treat men who are suffering from thrush on the penis.
Vaginal thrush is the common term for infections of the vagina with Candida species of fungi, in particular Candida albicans. This infection causes inflammation and discharge from the vagina. In men it causes soreness and redness of the penis, tightness of the foreskin, or a white, odourless discharge from the penis.
Fluconazole kills the Candida fungi causing the thrush infection by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.
The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As fluconazole causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi and treats the infection.
Canesten oral capsule should be swallowed whole with a glass of water, either with or without food.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
If you are already taking any medicines, including herbal medicines and those bought without a prescription, you should check with your doctor or pharmacist before taking this medicine. This is so they can check that the combination is safe.
You should not take this medicine if you are taking any of the following medicines:
The following interactions can occur with longer courses of fluconazole. It is not clear if these interactions can happen with the single dose of fluconazole in this medicine. If you are taking any of the medicines mentioned below you should check with your doctor or pharmacist before taking Canesten oral capsule.
The anti-blood-clotting effect of anticoagulants such as nicoumalone and warfarin may be enhanced by fluconazole. As this may increase the risk of bleeding, people taking an anticoagulant medicine should have their blood clotting time (INR) monitored if they also take fluconazole.
The antibiotic rifampicin (used for tuberculosis) lowers the blood level of fluconazole. Your doctor may need to prescribe you a larger than normal dose of fluconazole if you need both these medicines.
Fluconazole may increase the blood levels of the following medicines:
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