Gadopentetate Dimeglumine

Generic Name: Gadopentetate Dimeglumine (GAD-oh-PEN-te-tate dye-MEG-loo-meen)Brand Name: Magnevist

Gadopentetate Dimeglumine increases the risk of a possibly severe and sometimes fatal condition called nephrogenic systemic fibrosis in certain patients with kidney problems. Nephrogenic systemic fibrosis results in thickening or hardening (fibrosis) of tissues in the body (eg, skin, muscle, internal organs). Before you receive Gadopentetate Dimeglumine , tell your doctor if you have a history of kidney or liver problems, liver transplant, or if you receive dialysis. Your doctor may need to perform kidney function tests before you receive Gadopentetate Dimeglumine . Tell your doctor right away if you develop redness, pain, or swelling of the skin; tightness or thickening of the skin; skin lesions; or muscle pain or weakness.

Gadopentetate Dimeglumine is used for:

Providing a better picture with magnetic resonance imaging (MRI).

Gadopentetate Dimeglumine is a diagnostic aid. When used with an MRI, it works by aiding in the detection of abnormalities in the brain, spinal cord, or whole body.

Do NOT use Gadopentetate Dimeglumine if:

  • you are allergic to any ingredient in Gadopentetate Dimeglumine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Gadopentetate Dimeglumine :

Some medical conditions may interact with Gadopentetate Dimeglumine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of kidney or liver problems or liver transplant, or if you receive dialysis
  • if you have anemia, asthma, blood problems (eg, blood clots, blood clotting problems, hemolysis, sickle cell anemia, other anemias), breathing problems, heart problems, kidney or liver problems, or seizures

Some MEDICINES MAY INTERACT with Gadopentetate Dimeglumine . However, no specific interactions with Gadopentetate Dimeglumine are known at this time.

Ask your health care provider if Gadopentetate Dimeglumine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Gadopentetate Dimeglumine :

Use Gadopentetate Dimeglumine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Gadopentetate Dimeglumine is usually given as an injection at your doctor's office, hospital, or clinic.
  • Do not use Gadopentetate Dimeglumine if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • If you miss a dose of Gadopentetate Dimeglumine , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Gadopentetate Dimeglumine .

Important safety information:

  • Gadopentetate Dimeglumine may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Gadopentetate Dimeglumine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Gadopentetate Dimeglumine should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Gadopentetate Dimeglumine while you are pregnant. Gadopentetate Dimeglumine is found in breast milk. If you are or will be breast-feeding while you are using Gadopentetate Dimeglumine , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Gadopentetate Dimeglumine :

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; minor pain, swelling, coldness, or redness at the injection site; nausea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; fast or irregular heartbeat; muscle weakness; numbness in an arm or leg; pain, redness, or swelling of the skin; severe stomach pain; sharp or crushing chest pain; skin lesions; sudden leg pain; sudden severe headache; sudden shortness of breath; tightness or thickening of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Gadopentetate Dimeglumine :

Gadopentetate Dimeglumine is usually handled and stored by a health care provider. If you are using Gadopentetate Dimeglumine at home, store Gadopentetate Dimeglumine as directed by your pharmacist or health care provider. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Gadopentetate Dimeglumine out of the reach of children and away from pets.

General information:

  • If you have any questions about Gadopentetate Dimeglumine , please talk with your doctor, pharmacist, or other health care provider.
  • Gadopentetate Dimeglumine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Gadopentetate Dimeglumine . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Magnevist Prescribing Information (FDA)
  • Magnevist Consumer Overview