Glycerol Phenylbutyrate

(GLI ser ole fen il BYOO ti rate)

Brand Names: U.S.

  • Ravicti

Is it safe for my child to take this drug?

  • Not if your child has an allergy to glycerol phenylbutyrate or any other part of this drug.
  • Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • Do not give this drug to an infant younger than 2 months of age.

Why does my child need this drug?

  • It is used to treat urea cycle problems.

How is this drug given?

  • This drug comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this drug is refilled.
  • Give this drug with food.
  • Measure liquid doses carefully.
  • Those who have feeding tubes may also use the liquid. Flush the feeding tube with 2 tablespoons (30 mL) of water after the drug is given and then repeat again with 2 tablespoons (30 mL) of water.
  • Have your child follow the diet plan your child's doctor told you about.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child's next dose, skip the missed dose and go back to your child's normal time.
  • Do not give 2 doses or extra doses.

What safety measures do I need to take when my child is using this drug?

  • Tell dentists, surgeons, and other doctors that your child is using this drug.
  • Have your child's blood work checked. Talk with your child's doctor.
  • Keep a list of all your child's drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child's doctor.
  • Check all drugs your child is taking with your child's doctor. This drug may not mix well with some other drugs.

What are some side effects of this drug?

  • Upset stomach or throwing up.
  • Belly pain.
  • Loose stools (diarrhea).
  • Not hungry.
  • Headache.

When do I need to call my child's doctor?

  • If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
  • If your child shows signs of a very bad reaction, call your child's doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
  • If your child has very bad dizziness or passing out.
  • If your child has a bad headache.
  • If your child has a change in thinking clearly and with logic.
  • If your child has memory problems or loss.
  • If your child has a change in hearing.
  • If your child has a change in taste.
  • If your child is feeling very tired or weak.
  • If your child has numbness or tingling in his/her hands or feet.
  • If your child gets a rash.
  • If your child’s health problem does not get better or if you believe your child’s health problem is worse.

How do I store and/or throw out this drug?

  • Store at room temperature.

General drug facts

  • If your child has a very bad allergy, he/she needs to wear an allergy ID at all times.
  • You may get this drug by drug order only. If there are refills, call your pharmacy. If your child does not have refills left, you may need to call your child's doctor.
  • Get rid of this drug when your child no longer needs it or if the drug is outdated.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
  • Do not share your child's drug with others and do not give anyone else's drug to your child.
  • Keep all drugs out of the reach of children and pets.
  • Keep a list of all your child's drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child's doctor.
  • These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
  • Talk with the doctor before giving your child any new drug, including OTC, natural products, or vitamins.
  • If you do not use a drug the right way, it may not be safe. Follow what your child’s doctor tells you.