GLYPRESSIN is used to treat bleeding veins in the lower end of the food-pipe in people with serious liver disease. When the liver is diseased, there is less blood flowing through it. This causes the blood to 'back up' in the veins in the lower end of the food pipe (and upper part of the stomach). The veins in the lining of the food pipe (and stomach) then become very large and stretched, much like varicose veins. Because the veins are also very fragile, they can rupture and then bleed severely into the stomach.
GLYPRESSIN contains terlipressin, a substance which acts to stop the bleeding by lowering the blood pressure in the veins of the food-pipe.
Ask your doctor if you have any questions about why GLYPRESSIN has been prescribed for you.
Your doctor may have prescribed it for another reason.
GLYPRESSIN is not addictive.
This medicine is available only with a doctor's prescription.
Do not use GLYPRESSIN if you have an allergy to terlipressin, the active ingredient, or to any of the other ingredients listed at the end of this leaflet.
Symptoms of an allergic reaction to GLYPRESSIN may include:
Do not use GLYPRESSIN if you are pregnant.
It may affect your developing baby if you are given it during pregnancy.
Do not use GLYPRESSIN if you are breast-feeding or planning to breast-feed.
It is not known if it passes into breast milk or is safe for use in infants.
Do not use GLYPRESSIN after the expiry date (EXP) printed on the pack.
If you use it after the expiry date has passed, it may not work as well.
Do not use GLYPRESSIN if the packaging is torn/damaged or shows signs of tampering.
Tell your doctor if you have allergies to:
Tell your doctor if you have or have had any medical conditions, especially the following:
Tell your doctor if you plan to have surgery.
If you have not told your doctor about any of the above, tell them before you start taking GLYPRESSIN.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop.
Some medicines and GLYPRESSIN may interfere with each other. These include:
Taking GLYPRESSIN with these medicines may cause your heart to slow down or beat irregularly.
These medicines may be affected by GLYPRESSIN, or may affect how well it works. You may need different amounts of your medicine, or you may need to take different medicines. Your doctor will advise you.
Your doctor and pharmacist may have more information on medicines to be careful with or avoid while taking GLYPRESSIN.
GLYPRESSIN is a medicine that is used in hospital and should only be administered by qualified staff.
Your doctor will give you the correct amount of GLYPRESSIN. The maximum dose is 1.7 mg every 4 hours.
Instructions for proper use of the drug intended for your doctor or nurse are included in the package insert.
GLYPRESSIN will be given to you by injection in one of your veins.
GLYPRESSIN is usually given for up to 48 hours.
As GLYPRESSIN is given to you under the supervision of your doctor, it is very unlikely that you will receive too much.
However, if you experience any side effects after you are discharged, immediately telephone your doctor, or the Poisons Information Centre (telephone Australia 13 11 26 or New Zealand 0800 POISON or 0800 764766), or go to Accident and Emergency at your nearest hospital.
You may need urgent medical attention.
Do this even if there are no signs of discomfort or poisoning.
You may need urgent medical attention.
If you receive too much GLYPRESSIN, you may experience any of the following:
Tell any other doctors, dentists, and pharmacists who are treating you that you are or have been treated with GLYPRESSIN.
If you are about to be started on any new medicine, tell your doctor, dentist or pharmacist that you are or have been treated with GLYPRESSIN.
Be sure to keep all your doctor's appointments.
Your doctor will want to do blood and other tests regularly to check on your progress and detect any unwanted side effects.
If you become pregnant while you are being given this medicine, stop taking/using it and tell your doctor or pharmacist immediately.
Some self-help measures suggested below may help your condition.
Talk to your doctor or pharmacist about them:
Tell your doctor or nurse immediately if you do not feel well after you have GLYPRESSIN.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.
The most frequently reported side effects are:
Other side effects include:
Tell your doctor or nurse if you notice anything else that is making you feel unwell.
Other side effects, not listed above, may also occur in some people.
If you have any queries about any aspect of your medicine, or any questions regarding the information in this leaflet, discuss them with your pharmacist what to do with any medicine that is left over.
GLYPRESSIN is given as intravenous injection:
Solution for Injectionthis is a clear, colourless solution containing 8.5mL of GLYPRESSIN solution (in an ampoule)
The active ingredient in GLYPRESSIN preparations is terlipressin.
Each ampoule of GLYPRESSIN Solution for Injection contains 0.85 mg terlipressin (equivalent to 1 mg of terlipressin acetate) in 8.5 mL solution.
Sodium chloride, Acetic acid, Sodium acetate trihydrate, Water for Injections
This medicine does not contain lactose, sucrose, gluten, tartrazine or any other azo dyes.