Treating a certain eye problem known as neovascular (wet) age-related macular degeneration (AMD).
Macugen is a selective vascular endothelial growth factor (VEGF) antagonist. It works by blocking a protein in the eye to slow or stop wet AMD.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Macugen . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Macugen . However, no specific interactions with Macugen are known at this time.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Macugen may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Macugen as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Macugen .
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; dizziness; headache; minor eye irritation; nausea.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding; blurred vision or other unusual changes in vision; chest pain; eye discharge; floaters, sparks, or lights in your vision; hearing loss; hoarseness; pain, redness, or swelling of your eye or eyelid; sensitivity to light.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.Proper storage of Macugen :
Store Macugen in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Keep Macugen out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Macugen . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.