Megace tablets contain the active ingredient megestrol acetate, which is a synthetic form of the naturally occurring female sex hormone, progesterone. It is used to treat women with certain hormone-dependant cancers.
Most breast cancers and cancers affecting the womb (endometrial cancers) are sensitive to the female sex hormone oestrogen, and their growth is increased in the presence of this hormone. Oestrogen binds to oestrogen receptors on the cancer cells and causes changes within the cells that result in faster growth of the cancer.
Megestrol opposes the action of oestrogen, which means that the growth and replication of cancer cells is disrupted.
Megace tablets must usually be taken for at least two months to see if they are being effective.
This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
There are no significant interactions reported with this medicine.
However, it is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to make sure that the combination is safe.
There are currently no other medicines available in the UK that contain megestrol acetate as the active ingredient.