Latest prescription information about Mephentermine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Generic Name : Mephentermine

Pronunciation : meh-FEN-ter-meen

Therapeutic Classification : Antihypotensives

ICD Code : Y52.9

Trade Name(s): 
India- Mephentine Amp, Mephentine Tab, Termin Vial.
International- Wyamine.

Why it is prescribed (Indications) : This medication is a cardiac stimulant, prescribed for hypotension (low blood pressure). 

When it is not to be taken (Contraindications): 

Contraindicated in patients with low blood pressure induced by chlorpromazine, concurrent use with any MAOIs ( Monamine Oxidase Inhibitors).

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : Adult: IV- Maintenance of BP in hypotensive state- 30-45 mg as single dose, repeated as necessary or followed by IV infusion of 0.1% mephentermine in 5% dextrose, rate and duration of administration will depend on patient's response. Hypotension secondary to spinal anesthesia in obstetric patients 15 mg as a single dose, repeat if needed.

How it should be taken : It comes as a tablet to take by mouth and also as an injection to be administered by a healthcare provider into the vein or muscle.

Warnings and Precautions : 
* Caution should be exercised in patients with history of heart disease, overactive thyroid, shock, high blood pressure, persistent and lasting illness, during pregnancy and breastfeeding.

Side Effects : 
Central Nervous System- Anxiety, confusion, drowsiness, incoherence and tremors.
Heart- High blood pressure, palpitations and fast heart rate.

Other Precautions : 
*Avoid excess dosage.

Storage Conditions : 
Oral: Store it at room temperature.
Injection: Normally handled and stored by healthcare practitioners.