How does it work?
Minims prednisolone are single use eye drops that contain the active ingredient prednisolone, which is a type of medicine called a corticosteroid (or steroid). Corticosteroids are used for reducing inflammation. (They should not be confused with another type of steroid, called anabolic steroids, that have gained notoriety due to their abuse by some athletes and body builders.)
Inflammation occurs as a result of allergy or irritation and is caused by the release of substances that are important in the immune system. These substances cause blood vessels to widen, resulting in the affected area becoming red, swollen, itchy and painful.
Corticosteroids are hormones produced naturally by the adrenal glands that have many important functions, including control of inflammatory responses. They work by acting within cells to decrease the release of inflammatory substances, thereby reducing swelling, redness and irritation.
Prednisolone is a synthetic corticosteroid that can be adminstered into the eyes to decrease local inflammation, for example caused by chemicals, heat, radiation, allergy, or foreign objects in the eye. It is sometimes used after eye surgery.
What is it used for?
- Short-term treatment of inflammatory conditions of the eyes (red, swollen and painful eyes).
- Minims prednisolone are for use in the eye only and should not be taken by mouth.
- Each minim is for single use only and should be discarded after use, even if some solution remains in the unit.
- These drops may cause your vision to blur temporarily after applying them into the eye. Do not drive or operate machinery until this has worn off.
- During the first two days of treatment you may be asked to apply these eye drops as often as every hour. Follow the instructions on your prescription label or given by your doctor carefully. It is important that you don't use these eye drops more or less often, or for a longer or shorter period of time, than you have been told by your doctor.
- Consult your doctor if after seven days of treatment with this medicine there is little or no improvement in your symptoms.
- These drops should not be used for longer than seven days, unless under expert supervision. If prolonged therapy is needed, you should have regular check-ups with your doctor so they can monitor you for adverse reactions.
- Intensive or prolonged application of corticosteroids to the eye may lead to an increase in the pressure inside the eye, glaucoma, damage to the optic nerve or the formation of cataracts. Your eye specialist will want you to have regular eye check-ups to monitor for these types of side effects if you use this medicine for long periods of time.
Use with caution in
- People with thinning of the cornea or sclera (the tissues which cover the outer surface of the eye).
Not to be used in
- Severe untreated bacterial eye infections.
- Viral infections of the eye, eg herpes simplex.
- Fungal infections of the eye.
- Tuberculosis of the eye.
- These drops should not be used to treat a red eye that has not been diagnosed by a doctor, as inappropriate use can cause blindness.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
- The safety of this medicine for use during pregnancy and breastfeeding has not been established. The medicine may be absorbed into the bloodstream after application into the eye. It is not recommended for use during pregnancy or breastfeeding unless the potential benefits to the mother outweigh any possible risks to the baby. Consult your doctor for further advice.
- If your doctor does ask you to use these eye drops while you are pregnant or breastfeeding, you can minimise the amount of medicine that is absorbed into your bloodstream and thus passes to your baby, by pressing on your tear duct while putting in the drops, and for a few minutes after. The tear duct is at the corner of the eye closest to your nose.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.
- Temporary blurred vision after putting the drops in the eye(s).
- Irritation, itching, stinging or burning sensation in the eye(s).
- Thinning of the cornea or sclera (the tissues which cover the outer surface of the eye).
- Increase in the pressure inside the eye (glaucoma) which may lead to problems with your sight. If you experience a feeling of pressure or pain in your eye(s) while using these eye drops you should tell your doctor straight away.
- If used in the eye frequently or for long periods of time, corticosteroids such as this one can cause partial loss of vision due to cloudiness in the lens of the eye (cataracts).
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines?
It is important to tell your doctor or pharmacist what medicines you are already using, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before using any new medicines while using this one, to make sure that the combination is safe.
If you are using any other types of eye drop you should administer them at least five minutes apart, to prevent the second drop washing away the first. Use gels or ointments last.
Other medicines containing the same active ingredient
Prednisolone has many different uses and comes in many different forms. The factsheets below contain information about prednisolone used in various areas of the body.
| Deltacortril gastro-resistant tablets ||Deltastab injection ||Predenema |
|Predfoam||Pred forte eye drops ||Predsol ear/eye drops |
|Predsol retention enema ||Predsol suppositories || |
Prednisolone tablets, enteric coated tablets and soluble tablets are also available without a brand name, ie as the generic medicine.