Minocycline

Generic Name: Minocycline (MIN-oh-SYE-kleen)Brand Name: Examples include Dynacin and Myrac

Minocycline is used for:

Treating infections caused by certain bacteria. It is also used with other medicines to treat severe acne. It may also be used for other conditions as determined by your doctor.

Minocycline is a tetracycline antibiotic. It works by slowing the growth of certain bacteria and allowing the body's immune system to destroy them.

Do NOT use Minocycline if:

  • you are allergic to any ingredient in Minocycline
  • you are taking acitretin, isotretinoin, methoxyflurane, or a penicillin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Minocycline :

Some medical conditions may interact with Minocycline . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney problems
  • if you have an autoimmune disorder (eg, lupus)

Some MEDICINES MAY INTERACT with Minocycline . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Aluminum salts (eg, carbonate) or cimetidine because they may decrease Minocycline 's effectiveness
  • Acitretin, anticoagulants (eg, warfarin), digoxin, ergot alkaloids and derivatives (eg, ergotamine), insulin, isotretinoin, methotrexate, methoxyflurane, or theophyllines because the risk of their side effects may be increased by Minocycline
  • Live oral typhoid vaccine, oral contraceptives (birth control pills), or penicillins because their effectiveness may be decreased by Minocycline

This may not be a complete list of all interactions that may occur. Ask your health care provider if Minocycline may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Minocycline :

Use Minocycline as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Minocycline by mouth. Do not take Minocycline with food or milk unless otherwise directed. Minocycline is sometimes taken with food or milk to reduce stomach upset. However, certain foods and milk may bind with Minocycline , preventing its full absorption. To avoid this problem, take Minocycline 2 to 3 hours before or after milk or any food containing magnesium, aluminum, or calcium.
  • If you also take bismuth salts (eg, bismuth subsalicylate), calcium salts (eg, calcium carbonate), colestipol, iron salts (eg, iron sulfate), magnesium, urinary alkalinizers (eg, daily antacids), sucralfate, vitamins/minerals, quinapril, didanosine, or zinc salts (eg, zinc sulfate), do not take them within 2 to 3 hours before or after taking Minocycline . Check with your doctor if you have questions.
  • Take Minocycline with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Minocycline .
  • To clear up your infection completely, take Minocycline for the full course of treatment. Keep taking it even if you feel better in a few days.
  • Minocycline works best if it is taken at the same time each day.
  • If you miss a dose of Minocycline , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Minocycline .

Important safety information:

  • Minocycline may cause dizziness, lightheadedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Minocycline with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Long-term or repeated use of Minocycline may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Minocycline may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Minocycline . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Minocycline only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Tell your doctor or dentist that you take Minocycline before you receive any medical or dental care, emergency care, or surgery.
  • Be sure to use Minocycline for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Minocycline . To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Use Minocycline with caution in the ELDERLY; they may be more sensitive to its effects.
  • Use Minocycline with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.
  • Minocycline should not be used in CHILDREN younger than 8 years old; safety and effectiveness in these children have not been confirmed. Using Minocycline in CHILDREN younger than 8 years old or in women during the last half of pregnancy may cause a permanent change in the tooth coloring of the child.
  • PREGNANCY and BREAST-FEEDING: Minocycline has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Minocycline while you are pregnant. Minocycline is found in breast milk. Do not breast-feed while taking Minocycline .

Possible side effects of Minocycline :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Changes in skin color; diarrhea; difficulty swallowing; dizziness; feeling of a whirling motion; lightheadedness; loss of appetite; nausea; sensitivity to sunlight; unsteadiness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding or discharge from the gums; bloody stools; blurred vision; decreased hearing; fever; headache; inflammation of the pancreas (stomach tenderness, nausea, vomiting, increased pulse rate); joint pain; muscle pain or weakness; pain, redness, or swelling in the mouth; painful sores in the mouth; redness or swelling of gums; red, swollen, blistered, or peeling skin; ringing in the ears; severe diarrhea; severe skin reaction to the sun; stomach cramps/pain; unusual tiredness or weakness; vaginal irritation or discharge.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org), or emergency room immediately.

Proper storage of Minocycline :

Store Minocycline at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Minocycline out of the reach of children and away from pets.

General information:

  • If you have any questions about Minocycline , please talk with your doctor, pharmacist, or other health care provider.
  • Minocycline is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Minocycline . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Minocycline Prescribing Information (FDA)
  • Minocycline Professional Patient Advice (Wolters Kluwer)
  • Dynacin capsules Prescribing Information (FDA)
  • Dynacin Detailed Consumer Information (PDR)
  • Dynacin Prescribing Information (FDA)
  • Minocin Prescribing Information (FDA)
  • Minocycline Capsules Prescribing Information (FDA)
  • Solodyn Prescribing Information (FDA)
  • Solodyn Consumer Overview