Molindone (moe-LIN-done)Brand Name:
Molindone is an antipsychotic. It may increase the risk of death when used to treat mental problems caused by dementia in elderly patients. Most of the deaths were linked to heart problems or infection. Molindone is not approved to treat mental problems caused by dementia.
Molindone is used for:
Treating schizophrenia. It may also be used for other conditions as determined by your doctor.
Molindone is an antipsychotic. It works in the brain to treat schizophrenia.
Do NOT use Molindone if:
- you are allergic to any ingredient in Molindone
- you have severe central nervous system depression (eg, severe drowsiness), are in a coma, or have been sedated
- you are taking sodium oxybate (GHB)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Molindone :
Some medical conditions may interact with Molindone . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of seizures, heart problems (eg, heart failure, slow or irregular heartbeat), abnormal electrocardiogram (ECG), heart attack, stroke, blood vessel problems, high or low blood pressure, or low white blood cell levels
- if you have a history of liver problems, stomach or bowel problems (eg, narrowing, blockage), neuroleptic malignant syndrome (NMS), suicidal thoughts or attempts, or alcohol abuse or dependence
- if you have Alzheimer disease, dementia, Parkinson disease, glaucoma, enlarged prostate, or urinary problems
- if you have had high blood prolactin levels or a history of certain types of cancer (eg, breast, pancreas, pituitary, brain), or if you are at risk for breast cancer
- if you are dehydrated, drink alcohol, or will be exposed to very high temperatures
Some MEDICINES MAY INTERACT with Molindone . Tell your health care provider if you are taking any other medicines, especially any of the following:
- Barbiturates (eg, phenobarbital), narcotics (eg, codeine), or sodium oxybate (GHB) because the risk of side effects, such as severe drowsiness, may be increased
- Tramadol because the risk of seizures may be increased
- Hydantoins (eg, phenytoin) or tetracyclines (eg, doxycycline) because their effectiveness may be decreased by Molindone
This may not be a complete list of all interactions that may occur. Ask your health care provider if Molindone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Molindone :
Use Molindone as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Molindone by mouth with or without food.
- Taking Molindone at the same time each day will help you remember to take it.
- Take Molindone on a regular schedule to get the most benefit from it.
- Continue to take Molindone even if you feel well. Do not miss any doses.
- If you miss a dose of Molindone , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Molindone .
Important safety information:
- Molindone may cause drowsiness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Molindone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Molindone ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Do NOT take more than the recommended dose without checking with your doctor.
- Do not become overheated in hot weather or while you are being active; heatstroke may occur.
- Neuroleptic malignant syndrome is a possibly fatal syndrome that can be caused by Molindone . Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
- Some patients who take Molindone may develop muscle movements that they cannot control. This is more likely to happen in elderly patients, especially women. The chance that this will happen or that it will become permanent is greater in those who take Molindone in higher doses or for a long time. Muscle problems may also occur after short-term treatment with low doses. Tell your doctor at once if you have muscle problems with your arms; legs; or your tongue, face, mouth, or jaw (eg, tongue sticking out, puffing of cheeks, mouth puckering, chewing movements) while taking Molindone .
- Molindone may increase the amount of a certain hormone (prolactin) in your blood. Symptoms may include enlarged breasts, missed menstrual period, decreased sexual ability, or nipple discharge. Contact your doctor right away if you experience any of these symptoms.
- Molindone may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
- Molindone may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
- Lab tests, including complete blood cell counts, may be performed while you use Molindone . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Molindone with caution in the ELDERLY; they may be more sensitive to its effects, especially involuntary muscle movements.
- Molindone should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Molindone while you are pregnant. It is not known if Molindone is found in breast milk. If you are or will be breast-feeding while you use Molindone , check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Molindone :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; drowsiness; dry mouth; increased saliva production; nausea; restlessness.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); altered mental abilities, including lack of response to your surroundings; blurred visions or vision changes; dark urine; decreased urination; enlarged breasts; exaggerated sense of well-being; fast or irregular heartbeat; fever, chills, or persistent sore throat; hyperactivity; increased sweating; menstrual changes; muscle problems of the head or neck (eg, involuntary tongue movement, neck muscle spasms, tightness in the throat, trouble speaking or swallowing); new or worsening mental or mood changes (eg, aggression, agitation, depression, severe anxiety); nipple discharge; prolonged, painful erection; seizures; stiff or rigid muscles; suicidal thoughts or attempts; tremor; uncontrolled muscle movements (eg, arm or leg movements, twitching of the face, jerking or twisting); yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include involuntary, uncontrolled muscle movements; loss of consciousness; severe or persistent drowsiness.Proper storage of Molindone :
Store Molindone at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Molindone out of the reach of children and away from pets.
- If you have any questions about Molindone , please talk with your doctor, pharmacist, or other health care provider.
- Molindone is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
This information is a summary only. It does not contain all information about Molindone . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
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