Naseptin nasal cream (Chlorhexidine, neomycin)

How does it work?

Naseptin nasal cream contains two active ingredients, chlorhexidine hydrochloride and neomycin sulphate.

Chlorhexidine gluconate has an antiseptic effect against a wide range of bacteria, yeasts, and some fungi and viruses. It kills the micro-organisms associated with various mild infections of the skin.

Neomycin sulphate is an antibiotic of the aminoglycoside type. It kills bacteria so is described as bactericidal in action. It works by entering bacterial cells and interfering with the production of proteins that the bacteria need to divide and multiply. This rapidly kills the bacteria.

This combination of ingredients is used to eradicate a type of bacteria called staphylococci from the inside of the nose. The cream is applied inside the nostrils both to treat and prevent nasal infections with this type of bacteria.

What is it used for?

  • Eradication of staphylococcal bacteria from the nostrils to prevent and treat infection.


  • You should not use this medicine immediately after washing your face, as soaps can reduce the action of the medicine.
  • Avoid bleaching fabrics which have been in contact with this cream, as brown stains may develop on the fabric.
  • Prolonged use of this medicine should be avoided, particularly in children, the elderly, and those with impaired hearing. Prolonged use of neomycin can lead to skin sensitivity, hearing problems or kidney problems.

Not to be used in

  • Allergy to chlorhexidine.
  • Allergyto peanuts or soya.
  • Allergy to the antibiotic neomycin

This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

  • There are no known harmful effects when this medicine is used by pregnant or breastfeeding mothers.

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

  • Skin irritation.

The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

There are no known interactions with this preparation.

Other medicines containing the same active ingredients

There are currently no other medicines available in the UK that contain both chlorhexidine and neomycin as the active ingredients.