Generic Name: nizatidine (ni ZA ti deen)Brand Names: Axid, Axid AR, Axid Pulvules
Nizatidine is in a group of drugs called histamine-2 blockers. Nizatidine works by decreasing the amount of acid the stomach produces.
Nizatidine is used to treat ulcers in the stomach and intestines. Nizatidine also treats heartburn and erosive esophagitis caused by gastroesophageal reflux disease (GERD), a condition in which acid backs up from the stomach into the esophagus.
Nizatidine may also be used for other purposes not listed in this medication guide.
Before taking nizatidine, tell your doctor if you have kidney or liver disease, or stomach cancer or other problems.
Avoid taking cimetidine (Tagamet), ranitidine (Zantac), or famotidine (Pepcid) while you are taking nizatidine, unless your doctor has told you to.Nizatidine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Nizatidine may be only part of a complete program of treatment that also includes changes in diet or lifestyle habits. Follow your doctor's instructions very closely.
Heartburn can be confused with early symptoms of heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, dizziness, pain spreading to the arm or shoulder, sweating, nausea or vomiting, and a general ill feeling.
Heartburn can be confused with early symptoms of heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, dizziness, pain spreading to the arm or shoulder, sweating, nausea or vomiting, and a general ill feeling.You should not use this medication if you are allergic to nizatidine or similar medications such as ranitidine (Zantac), cimetidine (Tagamet), or famotidine (Pepcid).
Ask a doctor or pharmacist if it is safe for you to take nizatidine if you have:
stomach cancer or other problems.
Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow your doctor's instructions.
Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.Although most ulcers heal within 4 weeks of nizatidine treatment, it may take up to 8 to 12 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.
This medication can cause you to have unusual results with certain lab tests. Tell any doctor who treats you that you are using nizatidine.
Nizatidine may be only part of a complete program of treatment that also includes changes in diet or lifestyle habits. Follow your doctor's instructions very closely.Store nizatidine at room temperature away from moisture, heat, and light. Throw away any unused nizatidine liquid that is older than 30 days.
See also: Nizatidine dosage in more detail
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include blurred vision, watery eyes, drooling, nausea, vomiting, or diarrhea.
Avoid taking cimetidine (Tagamet), ranitidine (Zantac), or famotidine (Pepcid) while you are taking nizatidine, unless your doctor has told you to.
pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
unusual bleeding, purple or red pinpoint spots under your skin;
skin rash, bruising, severe tingling, numbness, pain, muscle weakness;
fever, confusion; or
jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
nausea, vomiting, diarrhea;
runny or stuffy nose, cough
increased sweating; or
impotence or trouble having an orgasm.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Duodenal Ulcer:
Initial: 300 mg orally once a day at bedtime, or alternatively may use 150 mg orally twice a day.Maintenance: 150 mg orally once a day at bedtime.
Usual Adult Dose for Duodenal Ulcer Prophylaxis:
150 mg orally once a day at bedtime.
Usual Adult Dose for Gastric Ulcer:
300 mg orally once a day at bedtime, or alternatively may use 150 mg orally twice a day.
Usual Adult Dose for Erosive Esophagitis:
150 mg twice daily.
Usual Adult Dose for Gastroesophageal Reflux Disease:
150 mg twice daily.
Usual Adult Dose for Dyspepsia:
75 mg orally once or twice a day, taken right before or up to 60 minutes before eating.
Usual Pediatric Dose for Gastroesophageal Reflux Disease:
Investigational:Greater than 1 year (n=26): In mild to moderate reflux esophagitis: 10 mg/kg/day divided in two doses for 8 weeks.Greater than or equal to 4 to 11 years (n=104): 6 mg/kg/day divided in two doses, one dose given at 9 PM the night before surgery, and the other given at 6:30 AM the day of surgery.
Tell your doctor about all other medications you use, especially aspirin.
There may be other drugs that can interact with nizatidine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.