Orthoclone OKT 3 may cause serious allergic reactions. These may occur at any time while you use Orthoclone OKT 3 . It may also cause other serious and sometimes fatal effects, including heart and nervous system problems. Tell your doctor right away if you experience shortness of breath; chest pain; numbness of an arm or leg; sudden severe dizziness, headache, nausea, or vomiting; fainting; severe stomach pain; trouble speaking; vision changes (eg, light sensitivity or blindness); one-sided weakness; seizures; or paralysis after you receive Orthoclone OKT 3 .
You should only receive Orthoclone OKT 3 in a health care facility where you can receive proper treatment in case you have a severe allergic reaction or other severe side effects.
Your doctor may give you another medicine (methylprednisolone) to help lower the risk of certain severe side effects from Orthoclone OKT 3 .
Treating organ rejection after a kidney transplant. It is also used to treat organ rejection in patients with a heart or liver transplant if corticosteroids do not work well. It may also be used for other conditions as determined by your doctor.
Orthoclone OKT 3 is an immunosuppressant. It blocks the action of certain blood cells (eg, T lymphocytes) that can cause the body to reject the transplanted organ.
Contact your doctor or health care provider immediately if any of these apply to you.
Some medical conditions may interact with Orthoclone OKT 3 . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Orthoclone OKT 3 . Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Orthoclone OKT 3 may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Orthoclone OKT 3 as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about the proper use of Orthoclone OKT 3 .
Every medicine can cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Decreased appetite; diarrhea; dizziness; fatigue; flushing; headache; increased sweating; nausea; nervousness; tiredness or weakness; vomiting.Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or tarry stools; calf pain/tenderness; chest pain; confusion; decreased hearing/deafness; decreased urination; fainting; fast, slow, or irregular heartbeat; fever; hallucinations; hoarseness; mental or mood changes; muscle or joint aches or pain; neck soreness or stiffness; numbness of an arm or leg; one-sided weakness; paralysis; seizures; severe or persistent tiredness, weakness, nausea, vomiting, or diarrhea; shortness of breath; signs of infection (eg, chills, fever, sore throat); skin thickening, growths, or color change; speech changes; stomach pain; sudden severe dizziness or headache; swelling of the arms, legs, hands, or feet; tremor; trouble swallowing; uncontrolled muscle movements; unusual bruising or bleeding; unusual lumps; vision changes (eg, blindness, sensitivity to light); wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include decreased urination; diarrhea; fever; muscle pain; severe chills; shortness of breath; swelling; or vomiting.Proper storage of Orthoclone OKT 3 :
Orthoclone OKT 3 is usually handled and stored by a health care provider. If you are using Orthoclone OKT 3 at home, store Orthoclone OKT 3 as directed by your pharmacist or health care provider. Keep Orthoclone OKT 3 out of the reach of children and away from pets
This information is a summary only. It does not contain all information about Orthoclone OKT 3 . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.