Argipressin is similar to a naturally occuring hormone present in the body, also known as antidiuretic hormone (ADH) or vasopressin. ADH has two main effects in the body. Firstly, it acts on receptors in the kidney to retain water in the body, which helps to prevent excessive loss of water in the urine. Secondly, ADH causes narrowing of blood vessels (vasoconstriction), thereby limiting blood flow to a particular area of the body. In diabetes insipidus, there is a reduction in the function of ADH resulting in an increase in water lost from the body through urine. This results in the production of large amounts of dilute urine. Argipressin is used in the treatment of this disorder as it acts on the ADH receptors in the kidneys, mimicking the effect of ADH and preventing dehydration caused by excessive loss of water. Argipressin is commonly used to stop bleeding of varices in the food pipe (oesophagus). Varices are fragile distended veins that can occur in various parts of the body such as the oesophagus. This is caused by an increase in blood pressure in certain diseases such as severe liver disease. These fragile varices can rupture and lead to life threatening bleeding. Argipressin is therefore given to narrow blood vessels, and so restricting blood flow to the varices and stopping the bleeding.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
No known significant interactions have been reported.