Psoralen

Latest prescription information about Psoralen (PUVA). Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Generic Name : Psoralen (PUVA)

Therapeutic Classification : Antipsoriatics

ICD Code : Y56.9

Trade Name(s): 
India- Chromalin 10, Meladerm Tab, Melanocyl Oint, Melanocyl Soln, Melanocyl Tab, Melcyl Tab, Melonil Lotion, Melonil Tab, Manaderm.
International- Oxsoralen-Ultra, Uvadex, 8-MOP.

Other Name : Methoxsalen

Why it is prescribed (Indications) : 
This medication is also called as PUVA, a natural product, prescribed for eczema, psoriasis, vitiligo and mycosis fungoides. 

When it is not to be taken (Contraindications): 

Contraindicated in patients with skin cancer, children and hypersensitivity.

Dosage & When it is to be taken : 
The recommended dose is 20 mg or up to 600 mcg/kg 2-4 hour before measured periods of sunlight or UVA exposure twice weekly or on alternate days, with at least 48-hour intervals between doses.

How it should be taken : 
It comes as a tablet to take orally and lotion to apply topically, with food.

Warnings and Precautions : 
* Caution should be exercised in patients with history of liver impairment, photosensitivity, any allergy, during pregnancy and breastfeeding.
* Avoid exposure to sunlight and patient should wear sunglasses for 24 hours after administration.
* Cover male genital area during the treatment.
* Perform eye exam prior to therapy and at regular intervals thereafter, especially in those at increased risk of cataracts.

Side Effects : 
Nausea, sleeplessness, depression, nervousness, itching, redness, swelling, dizziness, headache, pimples, severe skin pain, pigmentation alteration of skin or nails and nail disorders.

Other Precautions : 
* Regularly examine patients for signs of malignant skin lesions.

Storage Conditions : 
Store it at room temperature.