Tacidine is used to treat both gastric ulcers and duodenal ulcers. A gastric ulcer occurs in the stomach. A duodenal ulcer occurs in the duodenum (which is a tube leading out of the stomach). The ulcers can be caused in part by too much acid being made in the stomach.
Tacidine is also used to help stop duodenal ulcers from coming back.
Tacidine is also used to treat reflux oesophagitis or reflux disease. This is caused by "washing back" (reflux) of food and acid from the stomach into the food pipe (also known as the oesophagus).
Reflux causes burning sensation in the chest rising up to the throat (heartburn) and most often occurs after eating or at night.
Tacidine belongs to a group of medicines called histamine H2 antagonist or histamine H2 blockers. These medicines work by reducing the amount of stomach acid produced which in turn reduces the pain and allows the ulcers and/or reflux disease to heal in most people.
Ask your doctor if you have any questions about why Tacidine has been prescribed for you.
Your doctor may have prescribed Tacidine for another reason.
Tacidine is not recommended for use in children, as the safety and effectiveness of Tacidine in children have not been established.
There is no evidence that Tacidine is addictive.
Do not take Tacidine if you have an allergy to:
Some of the symptoms of an allergic reaction may include:
Do not take Tacidine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.
Tell your doctor if you have or have had any of the following medical conditions:
Tell your doctor if you are pregnant or plan to become pregnant.
Your doctor will discuss the risks and benefits of taking Tacidine during pregnancy.
Tell your doctor if you are breastfeeding or wish to breastfeed.
Tacidine passes into breast milk and may affect your baby. Your doctor will discuss the risks and benefits of taking Tacidine when breastfeeding.
Tell your doctor if you plan to have surgery.
If you have not told your doctor about any of the above, tell them before you start taking Tacidine.
Some medicines and Tacidine may interfere with each other. These include:
These medicines may be affected by Tacidine or may affect how well it works. Your doctor can tell you what to do if you are taking any of these medicines.
They may differ from the information contained in this leaflet.
The dose varies from person to person:
Elderly people and those who have kidney problems may need lower doses.
Swallow the capsules whole with a full glass of water.
Take Tacidine at about the same time each day.
This will allow Tacidine to have its best effect and also help you remember when to take it.
Tacidine can be taken with or without food.
The 150 mg capsule is usually taken twice a day - one capsule in the morning and one capsule in the evening before you go to bed.
The 300 mg capsule is usually taken once daily at bedtime.
Continue taking Tacidine for as long as your doctor tells you.
Do not stop taking Tacidine, even if you feel better after a few days, unless advised by your doctor.
If you stop taking your medicine too early then your condition will not have been properly treated.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take the missed dose as soon as you remember, and then go back to taking your medicine as you would normally.
Do not take two doses at the same time to make up for the dose you missed.
This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Tacidine. Do this even if there are no signs of discomfort or poisoning.
You may need urgent medical attention.
If you are about to be started on any new medicine, tell your doctor or pharmacist that you are taking Tacidine.
Tell any other doctors, dentists and pharmacists who treat you that you are taking Tacidine.
If you become pregnant while taking Tacidine, tell your doctor immediately.
If you are going to have surgery, including dental surgery, tell your doctor or dentist that you are taking Tacidine.
Keep all of your doctor's appointments so that your progress can be checked.
Do not use Tacidine to treat any other complaints unless your doctor tells you to.
Do not give Tacidine to anyone else, even if they have the same condition as you.
Some self help measures suggested below may help your condition. Talk to your doctor or pharmacist about these measures and for more information.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Tacidine.
Tacidine is generally well tolerated, however, like all other medicines, Tacidine may have unwanted side effects in some people. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Do not be alarmed by the following list of side effects.
You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
The above list includes the more common side effects of your medicine. They are usually mild and short-lived.
Tell your doctor immediately if you notice any of the following:
The above list includes serious side effects that may require medical attention.
Tell your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following:
The above list includes very serious side effects. You may need urgent medical attention or hospitalisation.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
Other side effects not listed above may also occur in some people.
Keep your capsules in the pack until it is time to take them.
If you take the capsules out of the pack they may not keep well.
Keep your capsules in a cool dry place where the temperature stays below 30 degrees C.
Do not store Tacidine or any other medicine in the bathroom or near a sink.
Do not leave Tacidine in the car or on a window sill.
Heat and dampness can destroy some medicines.
Keep Tacidine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking Tacidine, or your capsules have passed their expiry date, ask your pharmacist what to do with any that are left over.
Tacidine capsules comes in 2 strengths:
Each Tacidine 150 capsule contains 150 mg of nizatidine.
Each Tacidine 300 capsule contains 300 mg of nizatidine.
The capsule also contains:
The capsules are gluten free.