Generic Name: triprolidine (trye PROE li deen)Brand names: Zymine, Zymine XR, Tripohist
Triprolidine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Triprolidine is used to treat symptoms of seasonal allergy, such as sneezing, itching, watery eyes, and runny nose.
Triprolidine may also be used for purposes other than those listed in this medication guide.
Before using triprolidine, tell your doctor if you are allergic to any drugs, or if you have:
an enlarged prostate; or
problems with urination.
If you have any of these conditions, you may not be able to use triprolidine, or you may need a dosage adjustment or special tests during treatment.FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Allergy medicine is usually taken only for a short time until your symptoms clear up.Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.
Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.Take triprolidine with food to lessen stomach upset.
This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.
If you need to have any type of surgery, tell the surgeon ahead of time if you have taken an allergy medicine within the past few days.Store this medicine at room temperature, away from heat, light, and moisture.
Since allergy medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Symptoms of a triprolidine overdose may include feeling restless or nervous, dizziness, drowsiness, dry mouth, seizure (black-out or convulsions), or coma.
Avoid becoming overheated or dehydrated during exercise and in hot weather.
Avoid using other medicines that make you sleepy (such as pain medication, sleeping pills, muscle relaxers, and medicine to treat depression or anxiety). They can add to sleepiness caused by an antihistamine.Avoid drinking alcohol while you are taking this medication. Alcohol can add to drowsiness caused by an antihistamine. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain type of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine such as diphenhydramine or chlorpheniramine.
feeling light-headed, fainting;
fast, pounding, or uneven heartbeat;
confusion, hallucinations, unusual thoughts or behavior;
severe dizziness, anxiety, restless feeling, or nervousness; or
urinating less than usual or not at all.
Keep using the medication and talk with your doctor if you have any of these less serious side effects:
dry mouth, stuffy nose;
change in appetite;
nausea, stomach pain;
problems with memory or concentration;
ringing in your ears; or
restless or excitability (especially in children).
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Before taking this medication, tell your doctor if you are using any of the following drugs:
a diuretic (water pill);
medication to treat irritable bowel syndrome;
bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);
aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others); or
an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).
If you are using any of these drugs, you may not be able to use triprolidine, or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect triprolidine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.