Vimovo is used to treat the symptoms of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Although Vimovo can relieve the symptoms of pain and inflammation (swelling, redness and heat), it will not cure your condition.
VIMOVO contains two different medicines called naproxen and esomeprazole. Each of these medicines works in a different way.
Naproxen belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). It works by reducing pain and inflammation.
Esomeprazole belongs to a group of medicines called proton pump inhibitors. It works by reducing the amount of acid your stomach produces. Esomeprazole helps to reduce the risk of ulcers and stomach problems developing in patients who need to take naproxen or other NSAIDs. Depending on the position of the ulcer it is called a gastric or duodenal ulcer. A gastric ulcer occurs in the stomach. A duodenal ulcer occurs in the duodenum which is the tube leading out of the stomach. These can be caused in part by too much acid being made in the stomach.
Your doctor may have prescribed Vimovo for another reason. Ask your doctor if you have any questions about why Vimovo has been prescribed for you.
Vimovo is not recommended for use in children, as there have been no studies of its effects in children.
There is no evidence that Vimovo is addictive.
This medicine is available only with a doctor's prescription.
Do not take Vimovo if:
1. you have an allergy to:
Many medicines used to treat headache, period pain and other aches and pains contain aspirin or NSAID medicines. If you are not sure if you are taking/using any of these medicines, ask your pharmacist.
Symptoms of an allergic reaction to these medicines may include:
2. you are in the last 3 months of pregnancy
3. you are vomiting blood or material that looks like coffee grounds
4. you are bleeding from the rectum (back passage), have black sticky bowel motions (stools) or bloody diarrhoea
5. you lose a lot of weight for no reason and have problems swallowing
6. you have a peptic ulcer (i.e. stomach or duodenal ulcer)
7. you have severe problems with your liver, kidney or heart
8. you are taking a medicine containing atazanavir, nelfinavir (both used to treat HIV infection) or cilostazol (for intermittent claudication)
9. you are taking another medication containing naproxen (e.g. Naprosyn) or esomeprazole (e.g. Nexium)
10. you have severe heart failure
11. you have a type of bleeding disorder or have bleeding on the brain
12. you are aged 18 or under
Do not take Vimovo if the packaging is torn or shows signs of tampering.
Do not take Vimovo if the expiry date (EXP) printed on the pack has passed.
If you take this medicine after the expiry date has passed, it may not work as well.
If you are not sure whether you should start taking/using Vimovo, contact your doctor.
Do not give Vimovo to children.
The safety and effectiveness of Vimovo in children have not been established.
Tell your doctor if:
1. you have any allergies to:
2. you are pregnant or intend to become pregnant
3. you are breast-feeding or plan to breast-feed
4. you have or have had any medical conditions, especially the following:
5. you currently have an infection
6. you plan to have surgery
7. you are a smoker
If you have not told your doctor about any of the above, tell them before you take Vimovo.
Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop.
Tell your doctor if you are taking another NSAID medicine or medicines containing proton pump inhibitors (e.g. esomeprazole) or H2 receptor antagonists (e.g. ranitidine) or other medicines which are used to treat gastric or duodenal ulcers, reduce the risk of these ulcers or to treat other stomach or digestive tract problems. If your doctor prescribes you Vimovo, you will most likely no longer need to take these medicines. If you continue to take them while taking Vimovo, you increase your chance of having an adverse effect. You should review the medicines you are currently taking with your doctor and follow their advice.
Some medicines may be affected by Vimovo, or may affect how well it works. These include:
If you are taking these medicines, you may need to take different amounts of your medicine, or you may need to take different medicines. Your doctor will advise you.
Your doctor and pharmacist may have more information on medicines to be careful with or avoid while taking Vimovo.
Take one tablet twice daily.
Follow all directions given to you by your doctor and pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the box/bottle, ask your doctor or pharmacist for help.
Swallow your tablets whole with a drink of water. Do not chew, split or crush the tablets.
It is important that you take your tablets whole for your medicine to work properly. Take your tablets at least 30 minutes before food.
Take the tablets at least 30 minutes before food.
Taking Vimovo with or just after food may reduce absorption of the medicine into your body.
Do not use Vimovo for longer than your doctor says.
As with other NSAID medicines, if you are using Vimovo for arthritis or ankylosing spondylitis, it will not cure your condition but it should help to control pain, swelling and stiffness. If you have arthritis or ankylosing spondylitis, Vimovo should be taken every day for as long as your doctor prescribes.
If you are not sure how long to take Vimovo, talk to your doctor.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking/using your tablets as you would normally.
Do not take/use a double dose to make up for the dose that you missed.
If you have trouble remembering to take/use your medicine, ask your pharmacist for some hints.
Immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26), or go to casualty at your nearest hospital, if you think that you or anyone else may have taken too much Vimovo. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Keep these telephone numbers handy.
If you take/use too much Vimovo, you may experience drowsiness, pain or tenderness in the stomach, stomach upset including nausea (feeling sick), vomiting, heartburn, indigestion or cramps.
If you become pregnant while taking Vimovo tell your doctor immediately.
If you are about to start taking any new medicine tell your doctor and pharmacist that you are taking/using Vimovo.
Tell all of the doctors, dentists, and pharmacists that are treating you that you are taking Vimovo.
If you are going to have surgery, tell your doctor you are taking Vimovo.
If you are going to have laboratory tests (e.g. blood or urine tests), tell your doctor you are taking Vimovo.
Vimovo can affect the results of these tests.
If you get an infection while using Vimovo, tell your doctor.
Vimovo may hide the some of the signs of an infection and may make you think, mistakenly, that you are better or that it is not serious. Signs of an infection may include fever, pain, swelling and redness.
Do not give Vimovo to anyone else, even if they have the same condition as you.
Do not use Vimovo to treat any other complaints unless your doctor tells you to.
Be careful driving or operating machinery until you know how Vimovo affects you.
As with other NSAID medicines, Vimovo may cause dizziness or light-headedness in some people. Make sure you know how you react to Vimovo before you drive a car, operate machinery, or do anything else that could be dangerous if you are dizzy or light-headed. If this occurs do not drive. If you drink alcohol, dizziness or light-headedness may be worse.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Vimovo.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor or pharmacist any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
These side effects are usually mild.
Tell your doctor immediately if you notice any of the following:
These are serious side effects. You may need urgent medical attention. Serious side effects are rare.
If any of the following happen, stop taking Vimovo and tell your doctor immediately or go to casualty at your nearest hospital:
These are very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are rare.
Occasionally, Vimovo may be associated with changes in your liver or blood, which may require your doctor to do certain blood tests.
Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything else that is making you feel unwell.
Ask your doctor or pharmacist if you don't understand anything in this list.
Do not be alarmed by this list of possible side effects. You may not experience any of them.
Keep your tablets in the pack until it is time to take them.
If you take the tablets out of the pack they will not keep well.
Keep the tablets in a cool dry place where the temperature stays below 30°C.
Do not store Vimovo or any other medicine in the bathroom or near a sink. Do not leave it in the car or on window sills.
Heat and dampness can destroy some medicines.
Keep it where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking/using Vimovo or the tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.
Vimovo tablets are yellow and are printed with 500/20 in black ink Vimovo is available in plastic bottles of 6 or 60 tablets.
Vimovo tablets contain naproxen 500 mg and esomeprazole 20 mg (as magnesium trihydrate) as the active ingredients. Other (inactive) ingredients are:
Vimovo does not contain lactose, sucrose, gluten, tartrazine or any other azo dyes.