Xifaxan

Generic Name: Rifaximin (rif-AX-i-min)Brand Name: Xifaxan

Xifaxan is used for:

Treating travelers' diarrhea caused by certain strains of bacteria in patients 12 years of age and older. It may be used for other conditions as determined by your doctor.

Xifaxan is an antibiotic. It works by slowing down the bacteria's ability to reproduce, allowing the body to fight the infection more effectively.

Do NOT use Xifaxan if:

  • you are allergic to any ingredient in Xifaxan

Contact your doctor or health care provider right away if any of these apply to you.

Before using Xifaxan :

Some medical conditions may interact with Xifaxan . Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of severe diarrhea caused by antibiotics (pseudomembranous colitis)
  • if you have a fever or blood in the stool

Some MEDICINES MAY INTERACT with Xifaxan . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Delavirdine, gefitinib, and lamotrigine because their effectiveness may be decreased by Xifaxan

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xifaxan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Xifaxan :

Use Xifaxan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Xifaxan . Talk to your pharmacist if you have questions about this information.
  • Take Xifaxan by mouth with or without food.
  • Xifaxan works best if it is taken at the same time each day.
  • To clear up your infection completely, take Xifaxan for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of Xifaxan , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Xifaxan .

Important safety information:

  • Contact your health care provider at once if diarrhea symptoms get worse or persist for more than 24 to 48 hours, or if you develop a fever.
  • Dehydration from diarrhea may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous.
  • Long-term or repeated use of Xifaxan may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Be sure to use Xifaxan for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Xifaxan should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Xifaxan while you are pregnant. It is not known if Xifaxan is found in breast milk. Do not breast-feed while taking Xifaxan .

Possible side effects of Xifaxan :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; gas; headache; nausea; sensations of needing to empty the bowel; stomach pain; urgent bowel movements; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty swallowing or breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; flushing); bloody stools; chest pain; fainting; severe diarrhea.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Xifaxan :

Store Xifaxan at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), away from heat, moisture, and light. Brief excursions at temperatures between 59 and 86 degrees F (15 and 30 degrees C) are permitted. Do not store in the bathroom. Keep Xifaxan out of the reach of children and away from pets.

General information:

  • If you have any questions about Xifaxan , please talk with your doctor, pharmacist, or other health care provider.
  • Xifaxan is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Xifaxan . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Xifaxan Prescribing Information (FDA)
  • Xifaxan Consumer Overview
  • Xifaxan Detailed Consumer Information (PDR)
  • Xifaxan Advanced Consumer (Micromedex) - Includes Dosage Information
  • Rifaximin Professional Patient Advice (Wolters Kluwer)