Jaundice-associated conditions are diseases or conditions that cause yellow skin (jaundice).
Jaundice is a sign of liver, gallbladder, or certain blood disorders. The skin and the eyes become yellow due to the buildup of bilirubin in the skin and "white" of the eye (sclera).
Conditions associated with jaundice include:
- Hepatitis due to the effects of drugs (drug-induced hepatitis)
- Jaundice caused by reduced oxygen or blood flow to the liver (ischemic hepatitis)
- Viral hepatitis (hepatitis A, hepatitis B, hepatitis C, hepatitis D, and hepatitis E)
Gallbladder and bile duct disorders:
- Blockage of the bile ducts (by infection, tumor, biliary stricture or gallstones)
- Gallbladder and bile duct cancers
Primary biliary cirrhosis
Bile pools in the liver because of the effects of drugs (drug-induced cholestasis)
- Congenital disorders of bilirubin metabolism
- Bile pools in the liver during pregnancy (intrahepatic cholestasis of pregnancy)
- Dark urine
- Pale or clay-colored stools
- Yellow in the white part of the eyes (sclera)
- Yellow skin
Other symptoms depend on the specific disorder:
- Cancers may produce no symptoms, or there may be fatigue, weight loss, or other symptoms
- Hepatitis may produce nausea, vomiting, fatigue, or other symptoms
Exams and Tests
Physical examination will show:
- Liver swelling (possibly)
Specific tests vary, but will include blood liver function tests to determine how well the liver is working.
Other tests may include:
Abdominal CT scan
- CT scan-directed biopsy
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Percutaneous transhepatic cholangiogram (PTCA)
All jaundice-associated conditions need to be diagnosed and treated. In some cases, you will only need observation, but always talk to your health care provider.
The outcome varies.
Complications vary, but can include life-threatening liver failure.
When to Contact a Medical Professional
Contact your health care provider if you develop symptoms of jaundice.
Prevention depends on the disorderÂ thatÂ causes the jaundice.
Conditions associated with jaundice