ABISART HCT is used to treat hypertension (i.e. high blood pressure).
This medicine belongs to a group of medicines called angiotensin-II receptor antagonists. Angiotensin II is a substance produced in the body which causes blood vessels to tighten.
Irbesartan blocks angiotensin-II and therefore relaxes your blood vessels. This helps to lower your blood pressure.
Hydrochlorothiazide belongs to the class of medicines known as diuretics. Diuretics cause an increase in the volume of urine. They also help with lowering blood pressure particularly when combined with other blood pressure reducing medicines.
Your doctor may also have recommended that you adjust your life style to help to lower your high blood pressure (losing weight, avoiding smoking, reducing alcohol consumption and restricting the amount of salt in the diet). Your doctor may also have encouraged the practice of regular, mild (not strenuous) exercise such as walking, swimming, etc.
Ask your doctor if you have any questions about why this medicine has been prescribed for you.
Your doctor may have prescribed it for another reason.
This medicine is available only with a doctor's prescription.
This medicine may affect your ability to drive a car or operate machinery.
Do not take ABISART HCT if you are:
Some of the symptoms of an allergic reaction may include
Do not take this medicine if you are not producing urine.
Do not take this medicine if you are pregnant (or think you may be pregnant) or are planning to become pregnant.
It may affect your developing baby if you take it during pregnancy.
Do not breast-feed if you are taking this medicine.
It is not known if ABISART HCT passes into breast milk, therefore it is not recommended to be taken while you are breast-feeding.
Do not give this medicine to children.
Safety and effectiveness in children have not been established.
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.
Tell your doctor if you have or have had any of the following medical conditions:
Be sure you tell your doctor about any of these things before you take any ABISART HCT.
Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding.
Your doctor can discuss with you the risks and benefits involved.
When pregnancy is detected, ABISART HCT should not be used.
If you have not told your doctor about any of the above, tell him/her before you start taking ABISART HCT.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from a pharmacy, supermarket or health food shop.
Some medicines and ABISART HCT may interfere with each other. It is important that you tell your doctor if you are taking, or plan to take any of the following:
These medicines may be affected by ABISART HCT or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines or whether you should have check-ups or blood test more frequently.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.
Follow all directions given to you by your doctor and pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the box, ask your doctor or pharmacist for help.
ABISART HCT will usually be prescribed by your doctor if previous treatment does not produce a sufficient drop in your blood pressure. Your doctor will tell you how to switch from your previous treatment to ABISART HCT.
The usual dose of ABISART HCT is one tablet a day. The full blood pressure lowering effect should be reached 6-8 weeks after beginning treatment. If your blood pressure is not satisfactorily reduced with ABISART HCT, your doctor may prescribe another medicine to be taken with ABISART HCT.
If you do not understand the instructions on the box, ask your doctor or pharmacist for help.
Swallow the tablets whole with a full glass of water.
Take your medicine at about the same time each day.
Taking it at the same time each day will have the best effect. It will also help you remember when to take it.
It does not matter whether you take ABISART HCT tablets before or after food.
This medicine helps to control your condition, but does not cure it. It is important to keep taking your medicine even if you feel well.
Therefore ABISART HCT must be taken every day.
Continue taking ABISART HCT until your doctor tells you to stop.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for the dose you missed.
This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints.
Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much ABISART HCT. Do this even if there are no signs of discomfort or poisoning.
You may need urgent medical attention.
Symptoms of an overdose may include feeling lightheaded or dizzy.
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking ABISART HCT.
Tell any other doctors, dentists and pharmacists who treat you that you are taking this medicine.
If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine.
It may affect other medicines used during surgery.
If you become pregnant while taking this medicine, tell your doctor immediately.
If you are about to have any blood tests, tell your doctor that you are taking this medicine.
It may interfere with the results of some tests.
Keep all of your doctor's appointments so that your progress can be checked.
Standing up slowly, especially when you get up from bed or chairs, will help your body get used to the change in position and blood pressure. If this problem continues or gets worse, talk to your doctor.
Make sure you drink enough water during exercise and hot weather when you are taking ABISART HCT, especially if you sweat a lot.
If you do not drink enough water while taking ABISART HCT, you may faint or feel lightheaded or sick. This is because your body does not have enough fluid and your blood pressure is low. If you continue to feel unwell, tell your doctor.
If you have excessive vomiting and/or diarrhea while taking ABISART HCT, tell your doctor.
This can also mean that you are losing too much water and your blood pressure may become too low.
Do not take ABISART HCT to treat any other complaints unless your doctor tells you to.
Do not give your medicine to anyone else, even if they have the same condition as you.
Do not stop taking your medicine or change the dosage without checking with your doctor.
If you stop taking it suddenly, your condition may worsen.
Be careful driving or operating machinery until you know how ABISART HCT affects you.
As with many other medicines used to treat high blood pressure, ABISART HCT may cause dizziness or light-headedness in some people. Make sure you know how you react to ABISART HCT before you drive a car, operate machinery or do anything else that could be dangerous if you are dizzy or lightheaded.
Be careful when drinking alcohol while you are taking this medicine.
If you drink alcohol, dizziness or light-headedness may be worse.
If you feel light-headed, dizzy or faint when getting out of bed or standing up, get up slowly.
Hydrochlorothiazide contained in this medicine could produce a positive analytical result in antidoping test.
By following these simple measures, you can further reduce the risk from heart disease.
Know warning signs of heart attack and what to do:
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking ABISART HCT.
This medicine helps most people with high blood pressure, but it may have unwanted side effects in some people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.
Do not be alarmed by the following list of side effects.
You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you -
The above list includes the more common side effects of your medicine. They are usually mild and do not normally require treatment to be interrupted.
Tell your doctor immediately if you notice any of the following:
The above list includes serious side effects that may require medical attention. Serious side effects are rare.
If any of the following happen, stop taking ABISART HCT and tell your doctor immediately or go to Accident and Emergency at your nearest hospital:
The above list includes very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are very rare.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
Other side effects not listed above may also occur in some people.
Keep your tablets in the pack until it is time to take them.
If you take the tablets out of the pack they may not keep well.
Keep your tablets in a cool dry place where the temperature stays below 25°C.
Do not store ABISART HCT or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car.
Heat and dampness can destroy some medicines.
Keep it where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.
ABISART HCT 150/12.5 tablet contains 150 mg of irbesartan and 12.5 mg of hydrochlorothiazide -
Peach, oval, biconvex tablet debossed with M on one side of the tablet and I33 on the other side. Available in blister packs of 30 tablets.
ABISART HCT 300/12.5 tablet contains 300 mg of irbesartan and 12.5 mg of hydrochlorothiazide -
Peach, oval, biconvex tablet debossed with M on one side of the tablet and I34 on the other side. Available in blister packs of 30 tablets.
ABISART HCT 300/25 tablet contains 300 mg of irbesartan and 25 mg of hydrochlorothiazide -
Pink, oval, biconvex tablet debossed with M on one side of the tablet and I35 on the other side. Available in blister packs of 30 tablets.
ABISART HCT contains irbesartan and hydrochlorothiazide as the active ingredients.
It also contains the following inactive ingredients: