Latest prescription information about Acenocoumarol. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Generic Name : Acenocoumarol
Therapeutic Classification : Anticoagulants / Antithrombotics
ICD Code : Y44.2
India- Acitrom Tab, Nistrom Tab.
International- Acenox, Acitrom, Antitrom, Azecar, Cumarol, Mini-Sintrom.
Why it is prescribed (Indications) :
This medication is an anticoagulant, prescribed for thromboembolic disorders. It inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K
This medication is not advisable in patients with active bleeding or risk of serious bleeding, severe high blood pressure and pregnancy.
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Dosage & When it is to be taken :
Adult: PO- 4-12 mg on the 1st day and 4-8 mg on the 2nd day. Maintenance: 1-8 mg/day as a single dose.
How it should be taken :
It comes as a tablet to take by mouth, with food.
Warnings and Precautions :
* Caution should be exercised in patients with history of bleeding disorders, peptic ulcer, severe wounds, allergies, stroke, stomach infections, liver or kidney impairment, elderly, children and breastfeeding.
* Avoid alcohol consumption while taking this medication.
Side Effects :
Skin- Hair loss, rash, hives and itching.
Gastrointestinal- Nausea, vomiting and diarrhea.
Liver - Liver damage.
Potentially Fatal- Severe bleeding.
Other Precautions :
*Avoid excess dosage.
Storage Conditions :
Oral: Store it at room temperature (20-25°C) and in an airtight container.