AVAPRO is a trade name (manufacturer's name) for the medicine, irbesartan. This medicine is in the tablets your doctor has prescribed for you.
AVAPRO lowers high blood pressure, which doctors call hypertension
Your doctor measured your blood pressure and found it to be too high. Everyone has blood pressure. This pressure helps get your blood all around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension (high blood pressure) which means your blood pressure stays high, even when you are calm and relaxed.
There are usually no symptoms of high blood pressure. The only way of knowing that you have hypertension is to have your blood pressure checked on a regular basis. High blood pressure, if not treated, can damage blood vessels in several organs such as the heart, the kidneys, the brain and the eyes. This may lead to heart attacks, heart or kidney failure, strokes, or blindness. There are usually no symptoms of high blood pressure before damage occurs, so your doctor needs to measure your blood pressure to see if it is too high.
High blood pressure can be treated and controlled with medicines such as AVAPRO. Your doctor may also have recommended that you adjust your lifestyle to help to lower your high blood pressure (losing weight, avoiding smoking, reducing alcohol consumption and restricting the amount of salt in the diet). Your doctor may also have encouraged the practice of regular, mild (not strenuous) exercise such as walking, swimming, etc.
AVAPRO is also used in the treatment of kidney disease in patients with high blood pressure and type 2 diabetes.
AVAPRO belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin II is a substance produced in the body which causes blood vessels to tighten. AVAPRO blocks angiotensin-II and therefore relaxes your blood vessels. This helps to lower your blood pressure.
AVAPRO slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes.
Your doctor may have prescribed AVAPRO for another use. If you want more information, ask your doctor.
Do not take AVAPRO if:
Your baby may absorb this medicine in the womb and there is a possibility of harm to the baby.
It is not known if AVAPRO passes into breast milk, therefore it is not recommended to be taken while you are breast-feeding.
If you take this medicine after the expiry date has passed, it may not work.
If you are not sure if you should start taking AVAPRO, talk to your doctor.
AVAPRO should not be given to children.
Tell your doctor if:
Be sure you tell your doctor about any of these things before you take any AVAPRO.
Tell your doctor if you are taking or intend to take any other medicines, including medicines that you buy without a prescription from your pharmacy, supermarket or health food shop.
It is especially important that you tell your doctor if you are taking, or plan to take any of the following:
Your doctor will decide whether your treatment needs to be altered or whether you should have check ups or blood tests more frequently
The tablets should be taken regularly as directed by your doctor. The tablets should be swallowed with a glass of water.
Your doctor will tell you how many tablets to take each day.
Usually patients start with one 150 mg tablet once a day, however some patients may need a lower starting dose. Your doctor will tell you if this is necessary. The full blood pressure lowering effect of AVAPRO should be reached about 4-6 weeks after starting treatment.
Depending on how your blood pressure responds, your daily dose of AVAPRO may need to be increased. Most patients take either 150mg or 300mg each day.
In patients with high blood pressure and type 2 diabetes, 300mg once daily is the preferred maintenance dose for the treatment of associated kidney disease.
Follow all directions given to you by your doctor carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the box, ask your doctor or pharmacist for help.
You should try to take your daily dose of AVAPRO at about the same time each day. Taking your AVAPRO tablets at the same time each day will have the best effect.
It does not matter whether you take AVAPRO tablets before or after food.
AVAPRO helps to control your high blood pressure, but it does not cure it. Therefore AVAPRO must be taken every day. Continue taking AVAPRO until your doctor tells you to stop.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and go back to taking your tablets as you would normally.
If you are not sure whether to skip the dose, talk to your doctor or pharmacist.
Do not take a double dose to make up for the missed dose.
If you have trouble remembering to take your tablets, ask your pharmacist for some hints.
Immediately telephone your doctor or Poisons Information Centre (telephone 131126) or go to the Accident and Emergency Department at your nearest hospital, if you or anyone else may have taken too much AVAPRO.
Do this even if there are no signs of discomfort or poisoning.
If you take too many AVAPRO tablets you will probably feel lightheaded or dizzy.
AVAPRO helps most people with high blood pressure, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking AVAPRO.
Tell your doctor if you notice any of the following and they worry you -
Tell your doctor immediately if you notice any of the following-
These are serious side effects. Skin rash and itchiness may be symptoms of an allergic reaction. You may need medical attention.
These side effects are not common.
If any of the following happen, stop taking AVAPRO and tell your doctor immediately or go to Accident and Emergency Department at your nearest hospital -
These are serious side effects. If you have them you may have had a serious allergic reaction to AVAPRO. You may need urgent medical attention or hospitalisation.
These side effects are very rare.
Other side effects not listed above may occur in some patients. If you notice any other unwanted effects, you should tell your doctor or pharmacist and ask for their advice.
Keep your AVAPRO tablets in the blister pack until it is time to take them.
If you take the tablets out of the blister pack they may not keep well.
Keep AVAPRO tablets in a cool dry place where the temperature stays below 25°C. Do not store AVAPRO or any other medicine in the bathroom or near a sink. Do not leave them near a radiator, in a car on hot days or on a window sill.
Heat and dampness can destroy some medicines.
Keep all medicines out of the reach of children.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking AVAPRO or the tablets have passed their expiry date, ask your pharmacist what to do with any tablets that are left over.
AVAPRO 75 mg tablets - white to off-white, oval, film-coated tablet with a heart shape on one side and "2871" on the other. Pack size: 30 tablets.
AUST R 101730
AVAPRO 150 mg tablets - white to off-white, oval, film-coated tablet with a heart shape on one side and "2872" on the other. Pack size: 30 tablets.
AUST R 101734
AVAPRO 300 mg tablets - white to off-white, oval, film-coated tablet with a heart shape on one side and "2873" on the other. Pack size: 30 tablets.
AUST R 101736
AVAPRO 75 mg tablets - 75 mg irbesartan per tablet.
AVAPRO 150 mg tablets - 150 mg irbesartan per tablet.
AVAPRO 300 mg tablets - 300 mg irbesartan per tablet.
AVAPRO tablets also contain carnauba wax, croscarmellose sodium, hypromellose, lactose, macrogol 3000, magnesium stearate, microcrystalline cellulose, silicon dioxide, and titanium dioxide.