C1 Inhibitor (Human)

Generic Name: C1 Inhibitor (Human) (C1 in-HIB-i-ter)Brand Name: Cinryze

C1 Inhibitor (Human) is used for:

Preventing angioedema attacks in patients with hereditary angioedema (HAE). It may also be used for other conditions as determined by your doctor.

C1 Inhibitor (Human) is a C1 inhibitor (human). It works by regulating the clotting and inflammatory reactions that can lead to local tissue swelling (angioedema).

Do NOT use C1 Inhibitor (Human) if:

  • you are allergic to any ingredient in C1 Inhibitor (Human)

Contact your doctor or health care provider right away if any of these apply to you.

Before using C1 Inhibitor (Human) :

Some medical conditions may interact with C1 Inhibitor (Human) . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood clots in your veins or lungs (eg, deep vein thrombosis, pulmonary embolism)

Some MEDICINES MAY INTERACT with C1 Inhibitor (Human) . However, no specific interactions with C1 Inhibitor (Human) are known at this time.

Ask your health care provider if C1 Inhibitor (Human) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use C1 Inhibitor (Human) :

Use C1 Inhibitor (Human) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with C1 Inhibitor (Human) . Talk to your pharmacist if you have questions about this information.
  • C1 Inhibitor (Human) is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using C1 Inhibitor (Human) at home, a health care provider will teach you how to use it. Be sure you understand how to use C1 Inhibitor (Human) . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use C1 Inhibitor (Human) if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • This product must be used within 3 hours after mixing.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of C1 Inhibitor (Human) , contact your doctor right away.

Ask your health care provider any questions you may have about how to use C1 Inhibitor (Human) .

Important safety information:

  • C1 Inhibitor (Human) may contain albumin, which comes from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used C1 Inhibitor (Human) .
  • C1 Inhibitor (Human) should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if C1 Inhibitor (Human) can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using C1 Inhibitor (Human) while you are pregnant. It is not known if C1 Inhibitor (Human) is found in breast milk. If you are or will be breast-feeding while you use C1 Inhibitor (Human) , check with your doctor. Discuss any possible risks to your baby.

Possible side effects of C1 Inhibitor (Human) :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; stuffy or runny nose.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in consciousness or speech; chest pain; dizziness or lightheadedness; fainting; fatigue; fever; numbness or tingling; severe or persistent headache; shortness of breath; sore throat; swelling or pain in the arms, legs, or stomach; weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include changes in consciousness or speech; chest pain; numbness or tingling; shortness of breath; swelling or pain in the arms, legs, or stomach.

Proper storage of C1 Inhibitor (Human) :

C1 Inhibitor (Human) is usually handled and stored by a health care provider. If you are using C1 Inhibitor (Human) at home, store C1 Inhibitor (Human) as directed by your pharmacist or health care provide. Keep C1 Inhibitor (Human) out of the reach of children and away from pets.

General information:

  • If you have any questions about C1 Inhibitor (Human) , please talk with your doctor, pharmacist, or other health care provider.
  • C1 Inhibitor (Human) is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about C1 Inhibitor (Human) . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.