Canesten 500mg pessary contains the active ingredient clotrimazole, which is an antifungal medicine used to treat infections with fungi and yeasts. Canesten pessary is a single dose treatment for vaginal thrush. (NB. Clotrimazole 500mg pessaries are also available without a brand name, ie as the generic medicine.)
Vaginal thrush is the common term for infections of the vagina with Candida species of fungi, in particular Candida albicans. This infection causes inflammation and discharge from the vagina.
Clotrimazole kills the Candida fungi causing the infection by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.
The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As clotrimazole causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi and treats the infection.
Canesten 500mg pessary is inserted high into the vagina to allow the clotrimazole to act directly in the area of infection. The pessary should be inserted into the vagina at bedtime using the applicator provided.
The single dose pessary should clear up the infection inside the vagina. However, you may also want to use a cream on the outside of the vagina (vulva and labia) to help relieve the external symptoms of the infection, such as itching, inflammation and soreness. Clotrimazole 1% or 2% cream are suitable for this. See the end of this factsheet for available products.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
This medicine is not known to affect other medicines.
For treating vaginal thrush:
|Canesten 10% VC||Canesten 100mg/200mg pessaries||Canesten combi pessary and cream|
|Canesten cream combi internal and external creams||Canesten internal cream||Canesten thrush cream|
For treating athlete's foot:
|Canesten AF cream||Canesten AF powder||Canesten AF spray|
For treating fungal skin infections:
|Canesten 1% cream||Canesten dermatological powder||Canesten dermatological spray|
|Canesten solution||Care clotrimazole cream 1%|