Generic Name: carbinoxamine, dextromethorphan, and phenylephrine (car bih NOX a meen, dex tro meh THOR fan, and feh nill EFF rin)Brand names: Dacex-A, DMax Syrup, X-Hist DM, XiraHistDM, TriTuss-A Drops, DMax Pediatric Drops
Carbinoxamine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
Carbinoxamine, dextromethorphan, and phenylephrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.
Carbinoxamine, dextromethorphan, and phenylephrine may also be used for purposes other than those listed in this medication guide.
Call your doctor if you have a fever, or if your symptoms get worse or do not improve after taking this medicine for 7 days.
Do not take this product for cough caused by smoking, asthma, or emphysema. Do not take this medicine if your cough produces a lot of mucus, unless your doctor has told you to.
Before taking this medication, tell your doctor if you are allergic to carbinoxamine, dextromethorphan, or phenylephrine, or if you have:
heart disease or high blood pressure;
a stomach ulcer or a stomach obstruction,
emphysema or chronic bronchitis; or
an enlarged prostate or urination problems.
If you have any of these conditions, you may not be able to use carbinoxamine, dextromethorphan, and phenylephrine, or you may need a dosage adjustment or special tests during treatment.FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Carbinoxamine, dextromethorphan, and phenylephrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Artifically-sweetened liquid forms of cough-and-cold medications may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.Take this medicine with a full glass of water. The effervescent tablet form of this medicine must be dissolved in water. Drop the tablet into 8 ounces (1 cup) of water and allow it to dissolve. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.
Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.
If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.Store the medication at room temperature away from moisture and heat.
See also: Carbinoxamine, dextromethorphan, and phenylephrine dosage in more detail
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Symptoms of a a carbinoxamine, dextromethorphan, and phenylephrine overdose may include confusion, blurred vision, dry mouth, nausea, vomiting, restlessness, hallucinations, fainting, and seizure (convulsions).
Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by carbinoxamine, dextromethorphan, and phenylephrine.
feeling light-headed, fainting;
urinating less than usual or not at all;
wheezing, tightness in your chest;
fast or pounding heartbeat; or
pale skin, easy bruising or bleeding.
Keep taking the medication and talk to your doctor if you have any of these less serious side effects:
lack of coordination;
stuffy nose, chest congestion;
sleep problems (insomnia);
feeling restless or excited (especially in children);
dry mouth or nose; or
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Usual Adult Dose for Cough and Nasal Congestion:
Carbinoxamine/dextromethorphan/phenylephrine 4 mg-15 mg-8 mg/5 mL oral liquid:10 mL orally every 6 hours not to exceed 4 doses daily.
Usual Pediatric Dose for Cough and Nasal Congestion:
Carbinoxamine/dextromethorphan/phenylephrine 1 mg-2 mg-2 mg/mL oral liquid:Carbinoxamine/dextromethorphan/phenylephrine 2 mg-3 mg-2 mg/mL oral liquid:Carbinoxamine/dextromethorphan/phenylephrine 2 mg-4 mg-2 mg/mL oral liquid:=2 yr to =2 yrs to =6 yrs to =12 yrs: 10 mL orally every 6 hours not to exceed 4 doses daily.
There may be other drugs that can affect carbinoxamine, dextromethorphan, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Carbinoxamine, dextromethorphan, and phenylephrine is available with a prescription under many different brand names. Generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.