Cernevit solution contains a range of vitamins; vitamin A (retinol), vitamin D3 (colecalciferol), vitamin E (alpha tocopherol), vitamin C (ascorbic acid), vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (nicotinamide or niacin), vitamin B6 (pyridoxine), vitamin B12 (cyanocabalamin), folic acid, pantothenic acid and biotin.
Vitamins are complex chemicals that are required for various body functions. The body cannot manufacture these chemicals itself (with the exception of vitamin D) and has to obtain them from the diet. Most are required in very small amounts.
A balanced diet that includes a variety of food is likely to provide adequate amounts of vitamins. However, a normal diet, ie where nutrients are absorbed from the gut, is not always possible. Inadequate intake of any vitamins over an extended period can lead to symptoms of deficiency. The type of symptoms depends on the vitamin concerned.
People who can't eat a normal diet include those with severe or prolonged disorders of the gut, people who have had major surgery, trauma, or burns, people in a coma, people who are refusing to eat and some people with kidney or liver failure. These people may not be able to get adequate nutrition either by eating, or by being fed through a feeding tube that goes into the stomach.
In these cases, nutrients are given by a drip into a vein (intravenous infusion). This may be in addition to normal eating or tube feeding (supplemental parenteral nutrition), or may be the sole source of nutrition (total parenteral nutrition or TPN).
Parenteral nutrition contains all the nutrients required by the body, such as fats, glucose, amino acids, electrolytes and trace elements. Cernevit is added to these intravenous feeding solutions to provide a source of vitamins. These are used by the body in the same way as vitamins obtained in a normal diet would be.
Cernevit is added to parenteral nutrition bags under aseptic (sterile) conditions in the pharmacy.
Your doctor and pharmacist will use the results of daily blood tests to check that the components added to the parenteral nutrition are necessary and appropriate.
This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, inform your doctor or pharmacist immediately.
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
It is important to tell your doctor or pharmacist what medicines you are taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Likewise, always ask your doctor or pharmacist before taking any new medicines during treatment with this one, to check that the combination is safe. Your doctor and pharmacist will always make sure that parenteral nutrition is compatible with any other medicines that you are being treated with.
Pyridoxine (vitamin B6) may reduce the effects of levodopa used to treat Parkinson's disease if the levodopa is used alone. However, levodopa is usually used in combination with either carbidopa (Sinemet) or benserazide (Madopar), and pyridoxine does not affect it in this case.
Folic acid may reduce the blood levels of the antiepileptic medicines phenobarbital, phenytoin and primidone. If you are having treatment with one of these antiepileptic medicines your doctor may need to increase the dose of the antiepileptic to make sure your seizures remain controlled.
There are currently no other intravenous vitamin supplements available in the UK that contain the same combination of vitamins as Cernevit.