Generic name: Ciprofloxacin hydrochlorideBrand names: Ciloxan

Why is Ciloxan prescribed?

Ciloxan is an antibiotic used in the treatment of eye infections. The ointment form of the drug is prescribed for eye inflammations. The solution can also be used to treat ulcers or sores on the cornea (the transparent covering over the pupil). Ciprofloxacin, the active ingredient, is a member of the quinolone family of antibiotics.

Most important fact about Ciloxan

Other forms of ciprofloxacin have been known to cause allergic reactions in a few patients. These reactions can be extremely serious, leading to loss of consciousness and cardiovascular collapse. Early warning signs include a skin rash, hives, and itching. Other symptoms may include swelling of the face or throat, shortness of breath, and a tingling feeling. If you develop any of these symptoms, seek emergency help immediately.

How should you take Ciloxan?

Ciloxan ointment should be applied in a ribbon on the inner eyelid. Ciloxan solution is administered with an eyedropper. Be careful to avoid touching the tip to the eye or any other surface. This could contaminate the solution.

  • If you miss a dose...Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and return to your regular schedule. Do not take two doses at once.
  • Storage instructions...Store at room temperature. Protect the solution from light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Ciloxan.

  • Side effects may include:Formation of crystals (with frequent application of solution only), local burning or discomfort

Why should Ciloxan not be prescribed?

If you've ever had an allergic reaction to a quinolone antibiotic such as ciprofloxacin hydrochloride, gatifloxacin, levofloxacin, moxifloxacin hydrochloride, norfloxacin, or ofloxacin, you should not use Ciloxan.

Special warnings about Ciloxan

The manufacturer of Ciloxan warns against wearing contact lenses while suffering an eye infection.

When treating corneal ulcers with Ciloxan solution, you may notice a white buildup on the surface of the ulcer. This usually disappears within a week or two, and is no cause for concern.

Prolonged use of Ciloxan sometimes promotes the growth of germs that are unaffected by the medication. The doctor will examine your eyes for signs of this development.

The ointment form of Ciloxan may slow down healing of the cornea and cause blurred vision.

Safety and effectiveness have not been established in children under 2 years of age for Ciloxan ointment, or under 1 year of age for the solution.

Possible food and drug interactions when taking Ciloxan

There is no information on interactions with Ciloxan. When taken internally, however, ciprofloxacin is known to interact with the following:


Special information if you are pregnant or breastfeeding

The effects of Ciloxan during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, alert your doctor immediately.

Researchers do not know whether Ciloxan makes its way into breast milk; but when ciprofloxacin is taken internally, it definitely appears. Be cautious if using Ciloxan while nursing.

Recommended dosage for Ciloxan


Eye Inflammation

Apply a 1/2-inch ribbon on the inner eyelid 3 times a day for the first 2 days, then 2 times a day for the next 5 days.


Eye Inflammation

Apply 1 or 2 drops every 2 hours for the first 2 days, then every 4 hours for the next five days.

Corneal Ulcers

Apply 2 drops in the affected eye every 15 minutes for the first 6 hours, then every 30 minutes for the rest of the first day. On the second day, apply 2 drops every hour. On the third through fourteenth days, apply 2 drops every 4 hours. Treatment can continue for more than 14 days if healing doesn't occur.


If you accidentally apply too many drops of solution, it can be flushed from the eye with warm water. The results of long-term overdosing are unknown. If you suspect a problem, check with your doctor.

  • Ciloxan Prescribing Information (FDA)
  • Ciloxan Concise Consumer Information (Cerner Multum)
  • Ciloxan Advanced Consumer (Micromedex) - Includes Dosage Information
  • Ciloxan Drops MedFacts Consumer Leaflet (Wolters Kluwer)